calcium channel blockers

Amlodipine - Diltiazem - Diltiazem - Felodipine - Nicardipine - Nidrendipine - Nifedipine - Nisoldipine - Verapamil      

Select
Display
Trial Studied trt Control trt patientstagsNCTROB Result

acute coronary syndrome

diltiazem
Göbel (Dutch study), 1995diltiazemplacebo -
DRS, 1986diltiazemplacebo -
nifedipine
HINT (nifedipine vs metoprolol), 1988nifedipinemetoprolol -

acute myocardial infarction

diltiazem
Machecourt, 1986diltiazemnegative
Gibson, 1986diltiazemplacebonegative
MDPIT, 1988diltiazemplacebonegative
Zannad, 1988diltiazemplacebonegative
nifedipine
Muller, 1984nifedipinenegative
Gordon, 1984nifedipinenegative
MI study group, 1979nifedipine -
Eisenberg, 1985nifedipineplacebonegative
Bradagan, 1986nifedipineplacebonegative
Jaffe, 1987nifedipineplacebonegative
Gottlieb, 1988nifedipineplacebonegative
Erbel, 1988nifedipineplacebonegative
SPRINT I, 1988nifedipineplacebonegative
SPRINT II, 1993nifedipineplacebonegative
Loogna, 1985nifedipineplacebonegative
TRENT (Wilcox), 1986nifedipineplacebonegative
Walker, 1988nifedipineplacebonegative
Sirnes, 1984nifedipineplacebonegative
verapamil
Bussman, 1984verapamilcontrolnegative
DAVIT I, 1984verapamilplacebo -
Crea, 1985verapamilplacebonegative
DAVIT II, 1990verapamilplacebonegative
CRIS, 1996verapamilplacebonegative
Danish study, 1984verapamilplacebonegative

heart failure

amlodipine
Packer, 1991amlodipinecontrolExploratory -
Smith, 1994amlodipinecontrolExploratory -
Udelson, 1996amlodipinecontrolExploratory -
Binkley, 1996amlodipinecontrolExploratory -
Ghali, 1997amlodipinecontrolExploratory -
PRAISE, 1996amlodipineplaceboLow risk of bias negative
PRAISE II , 2000AmlodipineplaceboLow risk of bias negative
diltiazem
Liao , 1998DiltiazemplaceboExploratory suggesting
DiDi, 1996diltiazemplaceboLow risk of bias negative
felodipine
VHeFT III, 1997felodipineplaceboExploratory negative
Kassis, 1987felodipineplaceboExploratory -
Littler, 1995FelodipineplaceboExploratory negative
Kassis, 1990felodipineplaceboExploratory -
Dunselman, 1990felodipineenalaprilExploratory -
De Vries, 1995felodipineenalaprilExploratory -
isradipine
Van den Toren, 1996isradipineplaceboExploratory -
mibefradil
MACH 1, 2000mibefradilplaceboLow risk of bias suggesting
nicardipine
Gheorghiade, 1991nicardipinecontrolExploratory -
Abrams, 1993nicardipinecontrolExploratory -
nisoldipine
Gaudron, 1996NisoldipineplaceboExploratory -
Rousseau, 1994nisoldipineplaceboExploratory -
Schofer, 1990nisoldipinecaptoprilExploratory -

post myocardial infarction

diltiazem
MDPIT, 1988diltiazemplacebonegative
nifedipine
MI study group, 1979nifedipine -
SPRINT I, 1988nifedipineplacebonegative
SPRINT II, 1993nifedipineplacebonegative
verapamil
DAVIT I, 1984verapamilplacebo -
DAVIT II, 1990verapamilplacebonegative
CRIS, 1996verapamilplacebonegative
Danish study, 1984verapamilplacebonegative