calcium channel blockers

Amlodipine - Diltiazem - Diltiazem - Felodipine - Nicardipine - Nidrendipine - Nifedipine - Nisoldipine - Verapamil      

Select            
Trial Studied trt Control trt patientstagsROB Trial result

acute coronary syndrome

diltiazem
Göbel (Dutch study), 1995   diltiazemplaceboLow risk of bias -
DRS, 1986   diltiazemplaceboLow risk of bias -
nifedipine
HINT (nifedipine vs metoprolol), 1988   nifedipinemetoprolol -

acute myocardial infarction

diltiazem
Machecourt, 1986   diltiazemnegative
Gibson, 1986   diltiazemplaceboLow risk of bias negative
MDPIT, 1988   diltiazemplaceboLow risk of bias negative
Zannad, 1988   diltiazemplaceboLow risk of bias negative
nifedipine
Muller, 1984   nifedipineLow risk of bias negative
Gordon, 1984   nifedipinenegative
MI study group, 1979   nifedipine -
Eisenberg, 1985     nifedipineplaceboLow risk of bias negative
Bradagan, 1986     nifedipineplaceboLow risk of bias negative
Jaffe, 1987   nifedipineplacebonegative
Gottlieb, 1988   nifedipineplaceboLow risk of bias negative
Erbel, 1988   nifedipineplaceboLow risk of bias negative
SPRINT I, 1988   nifedipineplaceboLow risk of bias negative
SPRINT II, 1993   nifedipineplaceboLow risk of bias negative
Loogna, 1985     nifedipineplaceboLow risk of bias negative
TRENT (Wilcox), 1986   nifedipineplaceboLow risk of bias negative
Walker, 1988     nifedipineplaceboLow risk of bias negative
Sirnes, 1984   nifedipineplaceboLow risk of bias negative
verapamil
Bussman, 1984   verapamilcontrolnegative
DAVIT I, 1984   verapamilplaceboLow risk of bias -
Crea, 1985   verapamilplacebonegative
DAVIT II, 1990   verapamilplaceboLow risk of bias negative
CRIS, 1996     verapamilplaceboLow risk of bias negative
Danish study, 1984     verapamilplaceboLow risk of bias negative

heart failure

amlodipine
Packer, 1991   amlodipinecontrolLow risk of bias -
Smith, 1994     amlodipinecontrolLow risk of bias -
Udelson, 1996   amlodipinecontrolLow risk of bias -
Binkley, 1996   amlodipinecontrolLow risk of bias -
Ghali, 1997   amlodipinecontrolLow risk of bias -
PRAISE, 1996     amlodipineplaceboLow risk of bias negative
PRAISE II , 2000     AmlodipineplaceboLow risk of bias negative
diltiazem
Liao , 1998     DiltiazemplaceboExploratory suggesting
DiDi, 1996     diltiazemplaceboLow risk of bias negative
felodipine
VHeFT III, 1997     felodipineplaceboLow risk of bias negative
Kassis, 1987   felodipineplaceboLow risk of bias -
Littler, 1995   FelodipineplaceboLow risk of bias negative
Kassis, 1990   felodipineplaceboLow risk of bias -
Dunselman, 1990   felodipineenalaprilLow risk of bias -
De Vries, 1995     felodipineenalaprilLow risk of bias -
isradipine
Van den Toren, 1996     isradipineplaceboLow risk of bias -
mibefradil
MACH 1, 2000     mibefradilplaceboLow risk of bias suggesting
nicardipine
Gheorghiade, 1991   nicardipinecontrolLow risk of bias -
Abrams, 1993   nicardipinecontrolLow risk of bias -
nisoldipine
Gaudron, 1996   NisoldipineplaceboExploratory -
Rousseau, 1994   nisoldipineplaceboLow risk of bias -
Schofer, 1990   nisoldipinecaptoprilLow risk of bias -

post myocardial infarction

diltiazem
MDPIT, 1988   diltiazemplaceboLow risk of bias negative
nifedipine
MI study group, 1979   nifedipine -
SPRINT I, 1988   nifedipineplaceboLow risk of bias negative
SPRINT II, 1993   nifedipineplaceboLow risk of bias negative
verapamil
DAVIT I, 1984   verapamilplaceboLow risk of bias -
DAVIT II, 1990   verapamilplaceboLow risk of bias negative
CRIS, 1996     verapamilplaceboLow risk of bias negative
Danish study, 1984     verapamilplaceboLow risk of bias negative