renin inhibitor

Aliskiren      

Select            
Trial Studied trt Control trt patientstagsROB Trial resultSerious adverse eventAdverse events leading to treatment discontinuation

heart failure

aliskiren
ASTRONAUT, 2013    NCTAliskirenplaceboLow risk of bias -

hypertension

aliskiren
AVOID, 2008      NCTaliskirenplaceboLow risk of bias negative-5%-11%
Schmieder (vs HCTZ), 2009     aliskirenhydrochlorothiazideLow risk of bias negative17%-30%
ALLAY, 2009      NCTaliskirenlosartanExploratory negative-24%-61%
Andersen, 2008     aliskirenramiprilLow risk of bias -