CEPT inhibition

Anacetrapib      

Select            
Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathCardiovascular death

cardiovascular prevention

anacetrapib
DEFINE, 2010    NCTanacetrapibplaceboExploratory negative38%300%
REALIZE, 2015      NCTanacetrapibplaceboLow risk of bias negative
torcetrapib
RADIANCE 1, 2007      NCTtorcetrapibplaceboExploratory negative-100%-100%
ILLUMINATE, 2007      NCTtorcetrapibplaceboLow risk of bias negative 58%40%
RADIANCE 2, 2007     torcetrapibplaceboLow risk of bias -
ILLUSTRATE, 2007      NCTtorcetrapibplaceboExploratory negative35%