vasodilators therapy

Buflomedil - Epoprostenol      

Select            
Trial Studied trt Control trt patientstagsROB Trial result

heart failure

epoprostenol
FIRST, 1997     epoprostenolstandard careExploratory -
hydralazine
Chatterjee, 1980   hydralazinecontrolExploratory -
Franciosa, 1982     hydralazineplaceboLow risk of bias -
Conradson , 1984   hydralazineplaceboExploratory -
Magorien , 1984     hydralazineplaceboLow risk of bias -
hydralazine-ISDN
VHeFT I (hydralazine ISDN), 1986   hydralazine-ISDNplaceboLow risk of bias negative
isosorbide dinitrate
NICE (Lewis), 1999     isosorbide dinitrateplacebo -
Franciosa , 1978   isosorbide dinitrateplaceboLow risk of bias -
nesiritide
NSGET (comparative trial), 2000     nesiritidecontrolLow risk of bias remark
FUSION 2, 2008        NCTnesiritideplaceboLow risk of bias remark
NSGET (efficacy trial), 2000     nesiritideplaceboLow risk of bias negative
PROACTION, 2003     nesiritideplaceboLow risk of bias negative
BNP-CARDS, 2007          NCTnesiritideplaceboLow risk of bias remark
ASCEND-HF, 2011        NCTnesiritideplaceboLow risk of bias negative
VMAC (intravenous neseritide), 2002      NCTnesiritideplaceboLow risk of bias remark
PRECEDENT, 2002      NCTnesiritidedobutamineExploratory remark
VMAC (24h), 2002      NCTnesiritidenitroglycerinRisk of bias negative
FUSION 1, 2004    NCTnesiritidestandard careLow risk of bias remark

peripheral vascular diseases

buflomedil
LIMB, 2008   buflomedilplaceboLow risk of bias suggesting
Diamantopoulos, 2001   buflomédilplacebo -
cilostazol
Beebe, 1999   cilostazolplacebo -
Dawson, 1998   cilostazolplacebo -
Money, 1998   cilostazolplacebo -
Strandness, 2002   cilostazolplacebo -
Dawson (cilostazol), 2000   cilostazolplacebo -
Elam, 1998     cilostazolplaceboLow risk of bias -
Otsuka 21-95-201   cilostazolplaceboLow risk of bias -
ginko biloba
Bauer, 1984   ginko bilobaplacebo -
Peters, 1998   ginko bilobaplacebo -
naftidrofuryl
Meehan, 1982   naftidrofuryl IVcontrol -
NIQOL germany, 1999   Naftidrofurylplacebo -
Clyne, 1980   naftidrofurylplacebo -
NIQOL belgium, 2001   naftidrofurylplacebo -
NCIS, 2001   naftidrofurylplacebo -
Testart, 1994   naftidrofuryl IVplacebo -
D'Hooge D, 2001   naftidrofuryl IVplacebo -
Negus, 1987   naftidrofuryl IVprostacyclin -
pentoxifylline
Dawson (pentoxifylline), 2000   pentoxifyllineplacebo -
APIC, 1989   pentoxifyllineplacebo -
Donaldson, 1984   pentoxifyllineplacebo -
Porter, 1982   pentoxifyllineplacebo -
Belcaro, 2002   pentoxifyllineplacebo -