death and events prevention

     

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Trial Studied trt Control trt patientstagsNCTROB Result

coronary artery disease

aspirin
CDPA, 1976aspirinplacebonegative
Cardiff I, 1974aspirinplacebonegative
Cardiff II, 1979aspirinplacebonegative
Vogel, 1979aspirinplacebosuggesting
AMIS, 1980aspirinplaceboNCT00000491suggesting
GAMIS, 1980aspirinplacebonegative
PARIS, 1980aspirinplacebonegative
JAMIS, 1999aspirinplacebosuggesting
SAPAT, 1992aspirinplaceboLow risk of bias suggesting
clopidogrel
CAPRIE, 1996clopidogrelaspirin -
ASCETclopidogrelaspirinNCT00222261Risk of bias negative
dipyridamol
Atlanta (Sbar), 1967dipyridamolcontrolExploratory negative
Becker, 1967dipyridamolcontrolExploratory negative
Wirecki, 1967dipyridamolcontrolExploratory negative
Igloe, 1970dipyridamolplaceboExploratory -
Zion, 1961dipyridamolplaceboExploratory -
Kinsella, 1962dipyridamolplaceboExploratory -
Leiberman, 1964dipyridamolplaceboExploratory -
Dewar, 1961dipyridamolplaceboExploratory -
Neumann, 1964dipyridamolplaceboExploratory -
Foulds, 1960dipyridamolplaceboExploratory -
PARIS, 1980dipyridamol + aspirinplacebonegative
PARIS-II, 1986dipyridamol + aspirinplacebonegative
PARIS, 1980dipyridamol + aspirinaspirinnegative
ticlopidine
Berglund, 1985ticlopidineplaceboExploratory negative