hormonal replacement therapy

     

Select            
Trial Studied trt Control trt patientstagsROB Trial result

cardiovascular prevention

estrogen
WAVE, 2002      NCTcombined estrogen and progestogenplaceboLow risk of bias negative
EAGAR, 2006      NCTcombined estrogen and progestogenplaceboLow risk of bias negative
HERS, 1998          NCTcombined estrogen and progestogenplaceboLow risk of bias negative
EVTET, 2000     combined estrogen and progestogenplaceboLow risk of bias negative
Hall, 1998     combined estrogen and progestogenplaceboLow risk of bias negative
WHI, 2002       combined estrogen and progestogenplaceboLow risk of bias negative
WHISP, 2006     combined estrogen and progestogenplaceboLow risk of bias negative
WISDOM, 2007     combined estrogen and progestogenplaceboLow risk of bias negative
ERA (estrogen plus medroxyprogesterone), 2000      NCTcombined estrogen and progestogenplaceboLow risk of bias negative
WELL-HART (estrogen-progestin), 2003      NCTcombined estrogen and progestogenplaceboLow risk of bias negative
Schulman (NHLBI) (estrogen-progestogen), 2002      NCTcombined estrogen and progestogenplaceboLow risk of bias -
ERA (estrogen alone ), 2000        NCTestrogenplaceboLow risk of bias negative
WELL-HART (estrogen alone), 2003      NCTestrogenplaceboLow risk of bias negative
Schulman (NHLBI) (estrogen alone), 2002      NCTestrogenplaceboLow risk of bias -
EPAT, 2001     estrogenplaceboLow risk of bias negative
ESPRIT, 2002     estrogenplaceboLow risk of bias negative
WEST, 2001     estrogenplaceboLow risk of bias negative