hormonal replacement therapy  

     

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Trial Studied trt Control trt patientstagsNCTROB Result

cardiovascular prevention

estrogen
WAVE, 2002combined estrogen and progestogenplaceboNCT00000555Low risk of bias negative
EAGAR, 2006combined estrogen and progestogenplaceboNCT00000605Low risk of bias negative
HERS, 1998combined estrogen and progestogenplaceboNCT00319566Low risk of bias negative
EVTET, 2000combined estrogen and progestogenplaceboLow risk of bias negative
Hall, 1998combined estrogen and progestogenplaceboLow risk of bias negative
WHI, 2002combined estrogen and progestogenplaceboLow risk of bias negative
WHISP, 2006combined estrogen and progestogenplaceboLow risk of bias negative
WISDOM, 2007combined estrogen and progestogenplaceboISRCTN63718836Low risk of bias negative
ERA (estrogen plus medroxyprogesterone), 2000combined estrogen and progestogenplaceboNCT00000549Low risk of bias negative
WELL-HART (estrogen-progestin), 2003combined estrogen and progestogenplaceboNCT00000559Low risk of bias negative
Schulman (NHLBI) (estrogen-progestogen), 2002combined estrogen and progestogenplaceboNCT00000601Low risk of bias -
ERA (estrogen alone ), 2000estrogenplaceboNCT00000549Low risk of bias negative
WELL-HART (estrogen alone), 2003estrogenplaceboNCT00000559Low risk of bias negative
Schulman (NHLBI) (estrogen alone), 2002estrogenplaceboNCT00000601Low risk of bias -
EPAT, 2001estrogenplaceboLow risk of bias negative
ESPRIT, 2002estrogenplaceboLow risk of bias negative
WEST, 2001estrogenplaceboLow risk of bias negative