insulin secretagogues - Meglitinides (glinides)

     

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Trial Studied trt Control trt patientstagsROB Trial result

diabetes type 2

mitiglinide
Gao      NCTmitiglinidenateglinideLow risk of bias -
Kumashiro, 2007     mitiglinideon top insulin glargine -
Kaku, 2009     mitiglinideplacebo (on top pioglitazone) -
nateglinide
Marre, 2002     nateglinideplaceboLow risk of bias -
Horton, 2000   nateglinideplaceboLow risk of bias -
Hanefeld, 1990   nateglinideplaceboLow risk of bias -
Saloranta, 2002   nateglinideplaceboLow risk of bias -
Mari, 2005   nateglinideplacebo -
Moses, 2001   nateglinideplaceboLow risk of bias -
Goldberg, 1998   repaglinideplaceboLow risk of bias -
Jovanovic, 2000   repaglinideplaceboLow risk of bias -
Bech, 2003   repaglinideplaceboLow risk of bias -
Li, 2009   nategliniderepaglinide -
Li, 2007   nategliniderepaglinide -
Ristic, 2006       nateglinidegliclazide (add on MET)Low risk of bias -
repaglinide
Moses, 1999     repaglinidecontrol (add on MET)Exploratory -
Landgraf, 1999   repaglinideglibenclamideLow risk of bias -
Marbury, 1999   repaglinideglibenclamide -
Wolffenbuttel, 1999   repaglinideglibenclamideLow risk of bias -
Madsbad, 2001   repaglinideglipizideLow risk of bias -
Lund, 2007   repaglinidemetforminLow risk of bias -
Raskin, 2001   repaglinideon top pioglitazone -
Raskin, 2001   repaglinideon top rosiglitazone -
Raskin, 2000   repaglinideon top troglitazone -
Chuang, 1999   repaglinideplacebo -
Goldberg, 1998   repaglinideplaceboExploratory -
Jovanovic, 2000   repaglinideplaceboLow risk of bias -
Landin-Olsson, 1999   repaglinideplacebo (on top bedtime NPH-insulin) -