insulin secretagogues - sulfonylureas

     

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Trial Studied trt Control trt patientstagsNCTROB Result

diabetes type 2

gliclazide
Ristic, 2006gliclazidenateglinide (add on MET) -
Matthews, 2005gliclazidepioglitazone (add on MET) -
Khanolkar, 2008gliclaziderosiglitazone (add on MET) -
glimepiride
Charpentier, 2001glimepiride monotherapymetformin -
glimeripide
Study 201 (Goldberg), 1996glimepirideplaceboExploratory -
Schade, 1998glimepirideplacebo -
Rosenstock, 1996glimepirideplacebo -
Luis Bautista, 2003glimepirideplacebo -
Kaneko, 1993glimepirideplacebo -
Study 202glimepirideplacebo -
Riddle, 1994glimepirideplacebo (add on insulin) -
LEAD-2 (Nauck) Sulf vs pbo, 2009glimepirideplacebo (add on MET)NCT00318461 -
Charpentier, 2001glimepirideplacebo (add on MET)negative
Draeger, 1996glimepirideglibenclamideLow risk of bias -
Protocol 311glimepirideglibenclamide -
Charpentier (301F)glimepiridegliclazide -
Inukai, 2005glimepiridegliclazide or glibenclamide -
Sonnenberg, 1997glimepiride odglimepiride bid -
Clark (301), 1997glimepirideglipizide -
Dills, 1996glimepirideglyburideExploratory -
glipizide
Goldsteinglipizidecontrol (add on MET) -
Rosenstock, 1993glipizideglyburide -
Birkeland, 1994glipizideglyburide -
Birkeland, 1994glipizideglyburide -
Simonson, 1997glipizideplacebo -
Testa, 1998glipizideplacebo -
Feinglos, 2005glipizide GITSplacebo (add on MET) -
Nauck, 2007glipizidesitagliptin (add on MET) -
glyburide
Hermann, 1991glibenclamidec (add on MET) -
DeFronzo, 1995glyburidec (add on MET) -
Erle, 1999glyburidec (add on MET) -
Marre (ass), 2002glibenclamidecontrol (add on MET) -
Tosi, 2003glibenclamidecontrol (add on MET) -
Blonde, 2002glyburidecontrol (add on MET) -
Garber, 2003glyburidecontrol (add on MET) -
Garber, 2002glyburideplacebo -
Vray, 1995glyburideplacebo -
Garber, 2006glibenclamiderosiglitazone (add on MET) -