antioxydants

Beta carotene - Vitamin c - Vitamin e      

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Trial Studied trt Control trt patientstagsNCTROB Result

cardiovascular prevention

beta carotene
ATBC beta carotene, 1994beta caroteneplaceboExploratory -
CARET beta carotene, 1996beta caroteneplaceboLow risk of bias negative
SCP beta carotene, 1990beta caroteneplacebonegative
NSCP (Green) beta carotene, 1999beta caroteneplaceboLow risk of bias negative
PHS beta carotene, 1996beta caroteneplaceboLow risk of bias suggesting
WHS beta carotene, 1999beta caroteneplaceboNCT00000479Low risk of bias negative
WACS beta-caroten, 2007beta caroteneplaceboNCT00000541Low risk of bias negative
ATBC 2nd prev subgroup (b carotene), 1998beta caroteneplaceboExploratory negative
vitamin c
WACS vitamin C, 2007vitamin CplaceboNCT00000541negative
PHS II vitamin C, 2008vitamin CplaceboNCT00270647Low risk of bias negative
vitamin e
GISSI, 1999vitamin EcontrolRisk of bias negative
PPP, 2001vitamin EcontrolRisk of bias negative
ATBC vitamin E, 1994vitamin EplaceboExploratory suggesting
CHAOS, 1996vitamin EplaceboExploratory suggesting
HOPE, 2000vitamin EplaceboLow risk of bias negative
AREDS, 2001vitamin EplaceboExploratory negative
Linxian, 1993vitamin Eplacebonegative
WACS vitamin E, 2007vitamin EplaceboNCT00000541Low risk of bias negative
PHS II vitamin E, 2008vitamin EplaceboNCT00270647Low risk of bias negative
WHS vitamin E, 2005vitamin EplaceboNCT00000479Exploratory negative
ASAP, 2000vitamin EplaceboExploratory negative
SPACE, 2000vitamin EplaceboLow risk of bias suggesting
HOPE renal insufficiency subgroup, 2004vitamin EplaceboExploratory negative
ATBC 2nd prev subgroup (vitamin E), 1998vitamin EplaceboExploratory negative

peripheral vascular diseases

vitamin e
Livingstone, 1958placebo -
Hamilton, 1953placebo -