insulin therapy

     

Select            
Trial Studied trt Control trt patientstagsROB Trial result

diabetes type 2

glargine
Rosenstock     glarginesuggesting
Eliaschewitz   glarginesuggesting
Massi     glarginesuggesting
Yki-Yarvinen     glarginenegative
Fonseca   glarginenegative
Pan     glargine -
Philis-Tsimikas     glarginesuggesting
Wang     glarginesuggesting
Yki-Yarvinen     glarginesuggesting
Yokoyama     glarginenegative
Fritche     morning insulin glarginebedtime insulin glarginesuggesting
Herman, 2005     lispro +glarginecontinuous infusion -
Owens, 2011     insulin glulisine + glargineglargine once dailyRisk of bias negative
OPAL, 2008     glulisine + glargineglulisine + glargine -
Riddle POC 4002 Glargine, 2003     glargineNPHRisk of bias -
HOE 901/3002, 2000     glargineNPH -
Riddle     glargineNPH + SUnegative
lixisenatide
GETGOAL-L    NCTlixisenatideglargine once dailyLow risk of bias -