insulin sensitizer - biguanides

     

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Trial Studied trt Control trt patientstagsNCTROB Result

diabetes type 2

metformin
Teupe, 1991metforminplacebonegative
Kooy (HOME), 2009metforminplaceboLow risk of bias suggesting
Campbell, 1994metforminGlipizidenegative
UKPDS (vs SU or INS)metforminSU/Insulinsuggesting