insulin sensitizer - biguanides

     

Select            
Trial Studied trt Control trt patientstagsROB Trial result

diabetes type 2

metformin
Teupe, 1991   metforminplacebonegative
Kooy (HOME), 2009     metforminplaceboLow risk of bias suggesting
Campbell, 1994   metforminGlipizidenegative
UKPDS (vs SU or INS)     metforminSU/Insulinsuggesting