endothelin receptor antagonist

     

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Trial Studied trt Control trt patientstagsNCTROB Result

acute heart failure

nesiritide
NSGET (comparative trial), 2000nesiritidecontrolLow risk of bias -
NSGET (efficacy trial), 2000nesiritideplaceboLow risk of bias negative
PROACTION, 2003nesiritideplaceboLow risk of bias negative
BNP-CARDS, 2007nesiritideplaceboNCT00186329Exploratory -
FUSION 2, 2008nesiritideplaceboNCT00091520Low risk of bias -
ASCEND-HF, 2011nesiritideplaceboNCT00475852Low risk of bias negative
VMAC (intravenous neseritide), 2002nesiritideplaceboNCT00083772Low risk of bias -
PRECEDENT, 2002nesiritidedobutamineNCT00270400Exploratory -
VMAC (24h), 2002nesiritidenitroglycerinNCT00083772Risk of bias negative
FUSION 1, 2004nesiritidestandard careNCT00270361Low risk of bias -