endothelin receptor antagonist

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultAll cause death30-day death

acute heart failure

nesiritide
NSGET (comparative trial), 2000     nesiritidecontrolLow risk of bias remark
NSGET (efficacy trial), 2000     nesiritideplaceboLow risk of bias negative48%
PROACTION, 2003     nesiritideplaceboLow risk of bias negative388%
BNP-CARDS, 2007          NCTnesiritideplaceboLow risk of bias remark
FUSION 2, 2008        NCTnesiritideplaceboLow risk of bias remark
ASCEND-HF, 2011        NCTnesiritideplaceboLow risk of bias negative -10%-10%
VMAC (intravenous neseritide), 2002      NCTnesiritideplaceboLow risk of bias remark
PRECEDENT, 2002      NCTnesiritidedobutamineExploratory remark
VMAC (24h), 2002      NCTnesiritidenitroglycerinRisk of bias negative56%
FUSION 1, 2004    NCTnesiritidestandard careLow risk of bias remark