B-Raf enzyme inhibitors  

Combo dabrafenib + trametinib - Vemurafenib      

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melanoma

combo dabrafenib + trametinib
COMBIE-ddabrafenib + trametinibdabrafenibNCT01584648 -
COMBI-Ddabrafenib and trametinibdabrafenib monotherapyNCT01584648Low risk of bias -
COMBI-AD ongoing dabrafenib and trametinibplaceboNCT01682083Low risk of bias ongoing
COMBI-v ongoing dabrafenib and trametinibvemurafenibNCT01597908 ongoing
sorafenib
NCI-2012-02978 ongoing paclitaxel, carboplatin, sorafenib tosylatecarboplatin, paclitaxelNCT00110019Low risk of bias ongoing
11718 ongoing Sorafenib and CarboplatinCarboplatin/PaclitaxelNCT00111007Low risk of bias ongoing
vemurafenib
GO27826 ongoing vemurafenibplaceboNCT01667419Low risk of bias ongoing