phosphodiesterase III inhibitors

Amrinone - Vesnarinone      

Select            
Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathSudden death

heart failure

amrinone
AMTG, 1985   AmrinoneplaceboLow risk of bias negative11%
Enoximone
WESG, 1991   EnoximoneplaceboLow risk of bias negative38%4%
EMTG, 1990   EnoximoneplaceboLow risk of bias negative 247%+Infini%
ESG, 2000     EnoximoneplaceboLow risk of bias negative-75%
Lardoux, 1987   EnoximoneplaceboLow risk of bias negative-20%
ESSENTIAL (I and II), 2009    NCTenoximoneplaceboLow risk of bias negative-2%
Cowley, 1994   EnoximoneplaceboLow risk of bias negative52%
EMOTE, 2007   enoximoneplaceboLow risk of bias -
Flosequinan
Cowley, 1993   FlosequinanplaceboLow risk of bias negative11%11%
FACET, 1993   FlosequinanplaceboLow risk of bias negative12%-100%
REFLECT, 1993   FlosequinanplaceboLow risk of bias negative 276%169%
REFLECT II, 1991   FlosequinanplaceboLow risk of bias negative11%
ibopamine
PRIME II, 1997     ibopamineplaceboLow risk of bias negative 20%50%
Milrinone
PROMISE, 1991   MilrinoneplaceboLow risk of bias negative 24%57%
MMTG, 1989   MilrinoneplaceboLow risk of bias negative133%
vesnarinone
OPC-8212 MRG, 1990   VesnarinoneplaceboLow risk of bias negative-100%
VEST, 1998     VesnarinoneplaceboLow risk of bias negative 16%26%
VSG, 1993     VesnarinoneplaceboLow risk of bias suggesting-61%-80%