phosphodiesterase III inhibitors  

Amrinone - Vesnarinone      

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Trial Studied trt Control trt patientstagsNCTROB Result

heart failure

amrinone
AMTG, 1985AmrinoneplaceboLow risk of bias negative
Enoximone
WESG, 1991EnoximoneplaceboLow risk of bias negative
EMTG, 1990EnoximoneplaceboLow risk of bias negative
ESG, 2000EnoximoneplaceboLow risk of bias negative
Lardoux, 1987EnoximoneplaceboLow risk of bias negative
ESSENTIAL (I and II), 2009enoximoneplaceboNCT00051285Low risk of bias negative
Cowley, 1994EnoximoneplaceboLow risk of bias negative
EMOTE, 2007enoximoneplaceboLow risk of bias -
EMPOWER ongoing enoximoneplacebo (on top metoprolol)NCT00077948Low risk of bias ongoing
Flosequinan
Cowley, 1993FlosequinanplaceboLow risk of bias negative
FACET, 1993FlosequinanplaceboLow risk of bias negative
REFLECT, 1993FlosequinanplaceboLow risk of bias negative
REFLECT II, 1991FlosequinanplaceboLow risk of bias negative
ibopamine
PRIME II, 1997ibopamineplaceboLow risk of bias negative
Milrinone
PROMISE, 1991MilrinoneplaceboLow risk of bias negative
MMTG, 1989MilrinoneplaceboLow risk of bias negative
vesnarinone
OPC-8212 MRG, 1990VesnarinoneplaceboLow risk of bias negative
VEST, 1998VesnarinoneplaceboLow risk of bias negative
VSG, 1993VesnarinoneplaceboLow risk of bias suggesting