beta-blockers

Acebutolol - Alprenolol - Atenolol - Betaxolol - Bisoprolol - Bucindolol - Carvedilol - Labetalol - Metoprolol - Metroprolol - Nebivolol - Oxprenolol - Pindolol - Practolol - Propranolol - Sotalol - Timolol - Various beta blockers      

Select            
Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathhospitalisation for heart failure

acute myocardial infarction

acebutolol
Azancot, 1982   Acebutololplacebonegative
APSI, 1990   Acebutolol placeboLow risk of bias suggesting-48%
alprenolol
Andersen , 1979   Alprenolol placeboLow risk of bias negative-3%
Wilhelmsson , 1974   Alprenolol placeboLow risk of bias negative-49%
atenolol
ISIS1 Collaborative Group , 1986   Atenololplacebonegative-5%
Van de Werf , 1993   Atenololplacebonegative-77%
Yusuf , 1980   Atenololplacebonegative-22%
betaxolol
Yang , 1987   Betaxololplacebonegative
carvedilol
Basu , 1997     Carvedilol placeboLow risk of bias suggesting
labetalol
Heber , 1987   Labetalolplacebonegative71%
metoprolol
MIAMI Trial Research Group , 1985   placebonegative-13%
Von Essen , 1982   placebonegative4%
TIMI IIB, 1989   placebonegative0%
Hjalmarson , 1981   MetoprololplaceboLow risk of bias suggesting-36%
LIT Research Group , 1987   Metoprolol placeboLow risk of bias negative-7%
Manger Cats , 1983   Metoprolol placeboLow risk of bias negative-42%
Rehnqvist , 1983   Metoprolol placeboLow risk of bias suggesting-23%
Salathia , 1985   MetoprololplaceboLow risk of bias suggesting-21%
Waagstein , 1975   Practololormetoprololplacebonegative
oxprenolol
CPRG , 1981   Oxprenololplacebonegative38%
Fuccella , 1968   Oxprenololplacebonegative79%
Lombardo , 1979   Oxprenololplacebonegative-31%
Wilcox , 1980   Oxprenololplacebonegative41%
EIS , 1984   Oxprenolol placeboLow risk of bias negative 30%
Schwartz (high risk and low risk) , 1992   Oxprenolol placeboLow risk of bias suggesting -52%
Taylor , 1982   Oxprenolol placeboLow risk of bias negative-7%
pindolol
Owensby , 1984   Pindololplacebonegative
Australian and Swedish study, 1983   Pindolol placeboLow risk of bias negative -3%
practolol
Evemy , 1978   Practololplacebonegative57%
Johansson , 1980   Practololplacebonegative16%
Macleod , 1980   Practololplacebonegative+Infini%
Snow , 1980   Practololplacebonegative12%
Thompson , 1979   Practololplacebonegative-18%
Multicentre international , 1975   Practolol placeboLow risk of bias suggesting-20%
propranolol
Aronow , 1997     Propranolol controlsuggesting-27%
Balcon , 1966   Propranololplacebonegative-3%
Barber , 1976   Propranololplacebonegative-25%
Clausen , 1966   Propranololplacebonegative-8%
Curtis , 1991   Propranololplacebonegative
Dotremont , 1968   Propranololplacebonegative-20%
Gupta , 1982   Propranololplacebonegative-100%
Gupta , 1984   Propranololplacebonegative
Hutton , 1979   Propranololplacebonegative
Kahler , 1968   Propranololplacebonegative-59%
Ledwich , 1968   Propranololplacebonegative-33%
Mueller , 1980   Propranololplacebonegative100%
Multicentre , 1966   Propranololplacebonegative19%
Nigam , 1983   Propranololplacebonegative
Norris , 1968     Propranololplacebonegative30%
Norris , 1978     Propranololplacebonegative
Norris , 1984   Propranololplacebonegative9%
Peter , 1978   Propranololplacebonegative-49%
Pitt , 1976   Propranololplacebonegative
Roberts , 1984   Propranololplacebonegative21%
Singh , 1985   Propranololplacebonegative
Sloman , 1967   Propranololplacebonegative-34%
Baber , 1980   Propranolol placeboLow risk of bias negative7%
BHAT , 1982    NCTPropranolol placeboLow risk of bias suggesting -26%
Hansteen , 1982   Propranolol placeboLow risk of bias suggesting -31%
Wilcox , 1980   Propranolol or atenolol placeboLow risk of bias suggesting-6%
sotalol
Lloyd , 1988   Sotalolplacebonegative
timolol
Campbell , 1984   Timololplacebonegative-53%
Federman , 1984   Timololplacebonegative+Infini%
ICSG , 1984   Timololplacebonegative-27%
Ranganathan , 1988   Timololplacebonegative-64%
Tonkin , 1981   Timololplacebonegative10%
UKCSG , 1983   Timololplacebonegative-21%
Norwegian Multicentre Study Group , 1981   Timolol placeboLow risk of bias suggesting -36%
xamoterol
McMurray , 1991   Xamoterolplacebonegative

heart failure

bisoprolol
CIBIS, 1994     bisoprololplaceboLow risk of bias suggesting-21%-34%
CIBIS II, 1999     bisoprololplaceboLow risk of bias suggesting-32%
CIBIS II (elderly subgroup), 1999       Bisoprololplacebosuggesting-30%
bucindolol
BEST, 2001    NCTbucindololplaceboLow risk of bias suggesting-8%-16%
Pollock, 1990   BucindololplaceboLow risk of bias -
Woodley, 1991   Bucindololplacebo -
Bristow, 1994   Bucindololplacebo -
MERIT-HF (elderly subgroup), 1999     Bucindololplacebosuggesting-30%
carvedilol
ANZ-HeFT, 1997         carvedilolplaceboLow risk of bias negative-23%-30%
COPERNICUS, 2002     carvedilolplaceboLow risk of bias suggesting-33%-33%
CAPRICORN, 2001   carvedilolplaceboLow risk of bias suggesting-22%-14%
Metra, 1994   carvedilolplacebo -
Olsen, 1995     carvedilolplacebo -
Krum, 1995     carvedilolplacebo -
Bristow (MOCHA), 1996     carvedilolplaceboLow risk of bias -
Parker, 1996       carvedilolplaceboLow risk of bias negative
Colucci, 1996     carvedilolplaceboLow risk of bias -
Cohn, 1997     carvedilolplacebo -
Carvedilol U.S. Trials (elderly subgroup), 1996     Carvedilolplacebosuggesting-55%
COPERNICUS (elderly subgroup), 2001     Carvedilolplacebosuggesting-25%
CARMEN (carvedilol alone), 2004   carvedilolenalaprilnegative-1%-25%
COMET, 2003   carvedilolmetoprololLow risk of bias suggesting-14%
metoprolol
MDC (Waagstein), 1993   metoprololplaceboLow risk of bias negative7%-26%
MERIT-HF, 1999       metoprololplaceboLow risk of bias suggesting-33%
Engelmeier, 1985   metoprololplacebo -
Fisher, 1994   metoprololplacebo -
Eichhorn, 1994   metoprololplacebo -
RESOLVD, 2000     metoprololplacebo -
BEST (elderly subgroup), 2001     Metoprololplacebonegative-9%
nebivolol
Lechat, 1991   Nebivololplacebo -
Wisenbaugh, 1993   NebivololplaceboLow risk of bias negative+Infini%
SENIORS, 2005     nebivololplaceboLow risk of bias -