Drug eluting stent

Biolimus eluting stent - Everolimus eluting stent - Paclitaxel eluting stent - Sirolimus eluting stent - Zotarolimus eluting stent      

Select            
Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathtarget lesion revascularisation

coronary artery disease

abciximab
Kim, 2010     abciximab-coated stentbare-metal stentExploratory -
biolimus eluting stent
LEADERS, 2008      NCTbiolimus eluting stentsirolimus eluting stentnegative-9%-13%
candesartan
SYNTAX (unprotected left main sub group), 2009     DESCABGRisk of bias suggesting
dactinomycin eluting stent
ACTION, 2004   dactinomycin eluting stentbare-metal stentsuggesting-56%-74%
drug-eluting stents
PASEO, 2009   drug-eluting stentsbare-metal stent -
DEDICATION, 2008      NCTdrug-eluting stentsbare-metal stentRisk of bias suggesting100%
GENIUS-STEMI, 2009     Genous stentbare-metal stentExploratory negative-Infini%
Boudriot, 2008   DESCABGExploratory negative-61%
FREEDOM, 2012      NCTPCI with drug-eluting stentsCABGRisk of bias negative
Hong, 2005     PCI withdrug-eluting stentsCABGRisk of bias -
everolimus eluting stent
FUTURE I, 2004     everolimus eluting stentbare-metal stentnegative+Infini%-44%
FUTURE II, 2006   everolimus eluting stentbare-metal stentLow risk of bias -
SPIRIT I, 2005    NCTeverolimus eluting stentbare-metal stentExploratory negative-81%
BASKET-PROVE (EES), 2010   everolimus eluting stentbare-metal stentsuggesting-27%
RESET, 2011    NCTeverolimus eluting stentsirolimus eluting stent -
PLATINUM, 2011      NCTeverolimus eluting stenteverolimus eluting stent -
SPIRIT II, 2006      NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias negative-54%
SPIRIT IV, 2010          NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting-17%-45%
SPIRIT III, 2008        NCTeverolimus eluting stentpaclitaxel eluting stentExploratory suggesting-2%-41%
COMPARE, 2009        NCTeverolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting21%-65%
SPIRIT III (small vessel subgroup), 2009     everolimus eluting stentpaclitaxel eluting stentExploratory suggesting+Infini%-90%
SORT OUT IV, 2012      NCTeverolimus eluting stentsirolimus eluting stentRisk of bias -
ISAR-TEST 4 (EES vs SES)     everolimus eluting stentsirolimus eluting stentsuggesting
paclitaxel
ISAR-DESIRE (PES vs PTCA), 2005     paclitaxel eluting stentballoon angioplastysuggesting-67%
TAXUS I, 2003     paclitaxel eluting stentbare-metal stentLow risk of bias negative-100%
TAXUS II, 2003      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-100%-71%
TAXUS IV, 2004        NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting11%-73%
SCORE, 2004   paclitaxel eluting stentbare-metal stentsuggesting +Infini%
TAXUS V (all patients), 2005    NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-11%-45%
TAXUS VI, 2005        NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-100%
PASSION, 2006     paclitaxel eluting stentbare-metal stentRisk of bias negative-30%-30%
HAAMU-STENT, 2006   paclitaxel eluting stentbare-metal stentExploratory negative114%
Erglis, 2007     paclitaxel eluting stentbare-metal stentsuggesting-6%-88%
HORIZONS-AMI Stent, 2008     paclitaxel eluting stentbare-metal stentsuggesting1%-41%
TAXUS II (diabetics), 2003     paclitaxel eluting stentbare-metal stentLow risk of bias suggesting-84%
TAXUS IV (diabetics), 2005      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-63%
TAXUS V (diabetics), 2005   paclitaxel eluting stentbare-metal stentLow risk of bias suggesting-46%
TAXUS VI (diabetics), 2005      NCTpaclitaxel eluting stentbare-metal stentLow risk of bias suggesting-80%
SOS, 2008        NCTpaclitaxel eluting stentbare-metal stentExploratory suggesting138%-83%
TAXUS V small vessels sub groups   paclitaxel eluting stentbare-metal stent -
ASPECT, 2003      NCTpaclitaxel, non-polymeric eluting stentbare-metal stentLow risk of bias suggesting+Infini%+Infini%
ELUTES, 2004     paclitaxel, non-polymeric eluting stentbare-metal stentnegative+Infini%+Infini%
DELIVER, 2004   paclitaxel, non-polymeric eluting stentbare-metal stentRisk of bias negative-75%-75%
PATENCY, 2002   paclitaxel, non-polymeric eluting stentbare-metal stentLow risk of bias negative-100%-100%
TAXUS V ISR, 2006      NCTpaclitaxel eluting balloonbrachytherapyRisk of bias -
SYNTAX, 2009          NCTpaclitaxel eluting stentCABGRisk of bias suggesting 25%132%
ISAR-test (diabetics), 2006     paclitaxel eluting stentsirolimus eluting stentRisk of bias -
sirolimus eluting stent
ISAR-DESIRE (SES vs PTCA), 2005     sirolimus eluting stentballoon angioplastysuggesting-33%
Kochiadakis, 2007     sirolimus eluting stentbare-metal stentExploratory -
RAVEL, 2002      NCTsirolimus eluting stentbare-metal stentLow risk of bias suggesting-2%-100%
SIRIUS, 2003            NCTsirolimus eluting stentbare-metal stentLow risk of bias suggesting64%-75%
C-SIRIUS, 2004      NCTsirolimus eluting stentbare-metal stentLow risk of bias suggesting-78%
E-SIRIUS, 2003      NCTsirolimus eluting stentbare-metal stentsuggesting102%-81%
SES-SMART, 2004     sirolimus eluting stentbare-metal stentsuggesting-100%-67%
DIABETES, 2005       sirolimus eluting stentbare-metal stentsuggesting-80%
Pache et al, 2005     sirolimus eluting stentbare-metal stentsuggesting40%-62%
PRISON II, 2006      NCTsirolimus eluting stentbare-metal stentRisk of bias suggesting-79%
SCANDSTENT, 2006      NCTsirolimus eluting stentbare-metal stentsuggesting-3%-92%
TYPHOON, 2006      NCTsirolimus eluting stentbare-metal stentsuggesting1%
SESAMI, 2007        NCTsirolimus eluting stentbare-metal stentRisk of bias suggesting-57%-61%
DECODE, 2005      NCTsirolimus eluting stentbare-metal stentsuggesting-100%-66%
SCORPIUS, 2007    NCTsirolimus eluting stentbare-metal stentsuggesting
MISSION, 2008   sirolimus eluting stentbare-metal stentRisk of bias suggesting-52%-68%
Ortolani et al, 2007     sirolimus eluting stentbare-metal stent -
Pasceri, 2003   sirolimus eluting stentbare-metal stent -
GISSOC II, 2010      NCTsirolimus eluting stentbare-metal stentExploratory suggesting
DEBATER (SES vs BMS), 2009   sirolimus eluting stentbare-metal stentsuggesting
BASKET-PROVE (SES), 2010   sirolimus eluting stentbare-metal stentRisk of bias suggesting-19%
Ravel (diabetics), 2004     sirolimus eluting stentbare-metal stentsuggesting-93%
SES-SMARt (diabetics), 2005     sirolimus eluting stentbare-metal stentsuggesting-100%-45%
DESSERT, 2008   sirolimus eluting stentbare-metal stentExploratory suggesting54%-80%
SIRIUS (diabetics), 2003     sirolimus eluting stentbare-metal stentLow risk of bias -
Díaz de la Llera, 2007     sirolimus eluting stentbare-metal stent -
RRISC, 2006    NCTsirolimus eluting stentbare-metal stentRisk of bias suggesting+Infini%-76%
SCANDSTENT (subgroup), 2006     sirolimus eluting stentbare-metal stentExploratory suggesting
CRISTAL    NCTsirolimus eluting stentPTCA -
RIBS-II, 2008   sirolimus eluting stentPTCAsuggesting-3%
SISR, 2007        NCTsirolimus eluting stentbrachytherapyRisk of bias suggesting-56%
PRECOMBAT, 2011    NCTsirolimus eluting stentCABG -
Thiele, 2009    NCTPCI withsirolimus ESMIDCABRisk of bias -
Tomai, 2008     sirolimus eluting stentpaclitaxel eluting stent -
TAXi, 2005     sirolimus eluting stentpaclitaxel eluting stentRisk of bias negative96%
ISAR-DESIRE (SES vs PES), 2005     sirolimus eluting stentpaclitaxel eluting stentsuggesting100%
ISAR-DIABETES, 2005     sirolimus eluting stentpaclitaxel eluting stentnegative-33%-47%
SIRTAX (Windecker), 2005     sirolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting-54%-42%
CORPAL, 2005   sirolimus eluting stentpaclitaxel eluting stentnegative-21%-26%
REALITY, 2006      NCTsirolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting74%-2%
ISAR-SMART 3, 2006      NCTsirolimus eluting stentpaclitaxel eluting stentnegative-23%-39%
Zhang (SES vs PES), 2006     sirolimus eluting stentpaclitaxel eluting stentExploratory negative-6%-28%
LONG DES II, 2006     sirolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting+Infini%-67%
PROSIT, 2006   sirolimus eluting stentpaclitaxel eluting stentnegative-18%-38%
SORT OUT II, 2008      NCTsirolimus eluting stent