Drug eluting stent  

Biolimus eluting stent - Everolimus eluting stent - Paclitaxel eluting stent - Sirolimus eluting stent - Zotarolimus eluting stent      

Trial Studied trt Control trt patientstagsNCTROB Result

coronary artery disease

Kim, 2010abciximab-coated stentbare-metal stentExploratory -
biolimus eluting stent
LEADERS, 2008biolimus eluting stentsirolimus eluting stentNCT00389220negative
SYNTAX (unprotected left main sub group), 2009DESCABGRisk of bias suggesting
dactinomycin eluting stent
ACTION, 2004dactinomycin eluting stentbare-metal stentsuggesting
drug-eluting stents
PASEO, 2009drug-eluting stentsbare-metal stent -
DEDICATION, 2008drug-eluting stentsbare-metal stentNCT00192868Risk of bias suggesting
ISAR-CABG ongoing drug-eluting stentsbare-metal stentNCT00611910 ongoing
GENIUS-STEMI, 2009Genous stentbare-metal stentExploratory negative
Boudriot, 2008DESCABGExploratory negative
Leipzig ongoing drug-eluting stentsCABGNCT00176397 ongoing
FREEDOM, 2012PCI with drug-eluting stentsCABGNCT00086450Risk of bias negative
Hong, 2005PCI withdrug-eluting stentsCABGRisk of bias -
VA CARDS ongoing PCI withdrug-eluting stentsCABGNCT00326196Risk of bias ongoing
everolimus eluting stent
FUTURE I, 2004everolimus eluting stentbare-metal stentnegative
FUTURE II, 2006everolimus eluting stentbare-metal stentLow risk of bias -
SPIRIT I, 2005everolimus eluting stentbare-metal stentNCT00180453Exploratory negative
BASKET-PROVE (EES), 2010everolimus eluting stentbare-metal stentISRCTN72444640suggesting
RESET, 2011everolimus eluting stentsirolimus eluting stentNCT01035450 -
PLATINUM, 2011everolimus eluting stenteverolimus eluting stentNCT00823212 -
SPIRIT II, 2006everolimus eluting stentpaclitaxel eluting stentNCT00180310Risk of bias negative
SPIRIT IV, 2010everolimus eluting stentpaclitaxel eluting stentNCT00307047Risk of bias suggesting
SPIRIT III, 2008everolimus eluting stentpaclitaxel eluting stentNCT00180479Exploratory suggesting
COMPARE, 2009everolimus eluting stentpaclitaxel eluting stentNCT01016041Risk of bias suggesting
SPIRIT III (small vessel subgroup), 2009everolimus eluting stentpaclitaxel eluting stentExploratory suggesting
SORT OUT IV, 2012everolimus eluting stentsirolimus eluting stentNCT00552877Risk of bias -
ISAR-TEST 4 (EES vs SES)everolimus eluting stentsirolimus eluting stentsuggesting
LEFT-MAIN-2 ongoing everolimus eluting stentzotarolimus eluting stentNCT00598637 ongoing
ISAR-DESIRE (PES vs PTCA), 2005paclitaxel eluting stentballoon angioplastysuggesting
TAXUS I, 2003paclitaxel eluting stentbare-metal stentLow risk of bias negative
TAXUS II, 2003paclitaxel eluting stentbare-metal stentNCT00299026Low risk of bias suggesting
TAXUS IV, 2004paclitaxel eluting stentbare-metal stentNCT00292474Low risk of bias suggesting
SCORE, 2004paclitaxel eluting stentbare-metal stentsuggesting
TAXUS V (all patients), 2005paclitaxel eluting stentbare-metal stentNCT00301522Low risk of bias suggesting
TAXUS VI, 2005paclitaxel eluting stentbare-metal stentNCT00297804Low risk of bias suggesting
PASSION, 2006paclitaxel eluting stentbare-metal stentISRCTN65027270Risk of bias negative
HAAMU-STENT, 2006paclitaxel eluting stentbare-metal stentExploratory negative
Erglis, 2007paclitaxel eluting stentbare-metal stentsuggesting
HORIZONS-AMI Stent, 2008paclitaxel eluting stentbare-metal stentsuggesting
TAXUS II (diabetics), 2003paclitaxel eluting stentbare-metal stentLow risk of bias suggesting
TAXUS IV (diabetics), 2005paclitaxel eluting stentbare-metal stentNCT00292474Low risk of bias suggesting
TAXUS V (diabetics), 2005paclitaxel eluting stentbare-metal stentLow risk of bias suggesting
TAXUS VI (diabetics), 2005paclitaxel eluting stentbare-metal stentNCT00297804Low risk of bias suggesting
SOS, 2008paclitaxel eluting stentbare-metal stentNCT00247208Exploratory suggesting
TAXUS V small vessels sub groupspaclitaxel eluting stentbare-metal stent -
BASKET-SAVAGE ongoing paclitaxel eluting stentbare-metal stentNCT00595647 ongoing
ASPECT, 2003paclitaxel, non-polymeric eluting stentbare-metal stentNCT00196079Low risk of bias suggesting
ELUTES, 2004paclitaxel, non-polymeric eluting stentbare-metal stentnegative
DELIVER, 2004paclitaxel, non-polymeric eluting stentbare-metal stentRisk of bias negative
PATENCY, 2002paclitaxel, non-polymeric eluting stentbare-metal stentLow risk of bias negative
TAXUS V ISR, 2006paclitaxel eluting balloonbrachytherapyNCT00287573Risk of bias -
SYNTAX, 2009paclitaxel eluting stentCABGNCT00114972Risk of bias suggesting
VELETI ongoing paclitaxel eluting stentmedical treatmentNCT00289835 ongoing
PEPCAD IV ongoing paclitaxel eluting balloonpaclitaxel eluting stentNCT00462631 ongoing
PERSEUS Workhorse, 2010 ongoing paclitaxel eluting stentpaclitaxel eluting stentNCT00484315 ongoing
ISAR-test (diabetics), 2006paclitaxel eluting stentsirolimus eluting stentRisk of bias -
FRE-RACE ongoing paclitaxel eluting stentsirolimus eluting stentNCT00130546 ongoing
COMBAT ongoing PCICABG ongoing
Korean Randomized Study ongoing PCICABG ongoing
sirolimus eluting stent
ISAR-DESIRE (SES vs PTCA), 2005sirolimus eluting stentballoon angioplastysuggesting
Kochiadakis, 2007sirolimus eluting stentbare-metal stentExploratory -
RAVEL, 2002sirolimus eluting stentbare-metal stentNCT00233805Low risk of bias suggesting
SIRIUS, 2003sirolimus eluting stentbare-metal stentNCT00232765Low risk of bias suggesting
C-SIRIUS, 2004sirolimus eluting stentbare-metal stentNCT00381420Low risk of bias suggesting
E-SIRIUS, 2003sirolimus eluting stentbare-metal stentNCT00235144suggesting
SES-SMART, 2004sirolimus eluting stentbare-metal stentsuggesting
DIABETES, 2005sirolimus eluting stentbare-metal stentsuggesting
Pache et al, 2005sirolimus eluting stentbare-metal stentsuggesting
PRISON II, 2006sirolimus eluting stentbare-metal stentNCT00258596Risk of bias suggesting
SCANDSTENT, 2006sirolimus eluting stentbare-metal stentNCT00151658suggesting
TYPHOON, 2006sirolimus eluting stentbare-metal stentNCT00232830suggesting
SESAMI, 2007sirolimus eluting stentbare-metal stentNCT00288210Risk of bias suggesting
DECODE, 2005sirolimus eluting stentbare-metal stentNCT00489164suggesting
SCORPIUS, 2007sirolimus eluting stentbare-metal stentNCT00495898suggesting
MISSION, 2008sirolimus eluting stentbare-metal stentISRCTN62825862Risk of bias suggesting
Ortolani et al, 2007sirolimus eluting stentbare-metal stent -
Pasceri, 2003sirolimus eluting stentbare-metal stent -
GISSOC II, 2010sirolimus eluting stentbare-metal stentNCT00220558Exploratory suggesting
DEBATER (SES vs BMS), 2009sirolimus eluting stentbare-metal stentsuggesting
BASKET-PROVE (SES), 2010sirolimus eluting stentbare-metal stentISRCTN72444640Risk of bias suggesting
Ravel (diabetics), 2004sirolimus eluting stentbare-metal stentsuggesting
SES-SMARt (diabetics), 2005sirolimus eluting stentbare-metal stentsuggesting
DESSERT, 2008sirolimus eluting stentbare-metal stentExploratory suggesting
SIRIUS (diabetics), 2003sirolimus eluting stentbare-metal stentLow risk of bias -
Díaz de la Llera, 2007sirolimus eluting stentbare-metal stent -
RRISC, 2006sirolimus eluting stentbare-metal stentNCT00263263Risk of bias suggesting
SCANDSTENT (subgroup), 2006sirolimus eluting stentbare-metal stentExploratory suggesting
BASKET-PROVE, 2008 ongoing sirolimus eluting stentbare-metal stent ongoing
FOCUS ongoing sirolimus eluting stentcutting ballon angioplastyNCT00485004 ongoing
CRISTALsirolimus eluting stentPTCANCT00323895 -
RIBS-II, 2008sirolimus eluting stentPTCAsuggesting
SISR, 2007sirolimus eluting stentbrachytherapyNCT00231257Risk of bias suggesting
PRECOMBAT, 2011sirolimus eluting stentCABGNCT00422968 -
MIDCAB Versus DES in Proximal LAD Lesions ongoing sirolimus eluting stentCABGNCT00299429 ongoing
Munich Study ongoing sirolimus eluting stentCABG ongoing
Gao ongoing sirolimus eluting stentFirebird eluting stentNCT00887211 ongoing
Thiele, 2009PCI withsirolimus ESMIDCABNCT00299429Risk of bias -
Tomai, 2008sirolimus eluting stentpaclitaxel eluting stent -
TAXi, 2005sirolimus eluting stentpaclitaxel eluting stentRisk of bias negative
ISAR-DESIRE (SES vs PES), 2005sirolimus eluting stentpaclitaxel eluting stentsuggesting
ISAR-DIABETES, 2005sirolimus eluting stentpaclitaxel eluting stentnegative
SIRTAX (Windecker), 2005sirolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting
CORPAL, 2005sirolimus eluting stentpaclitaxel eluting stentnegative
REALITY, 2006sirolimus eluting stentpaclitaxel eluting stentNCT00235092Risk of bias suggesting
ISAR-SMART 3, 2006sirolimus eluting stentpaclitaxel eluting stentNCT00146575negative
Zhang (SES vs PES), 2006sirolimus eluting stentpaclitaxel eluting stentExploratory negative
LONG DES II, 2006sirolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting
PROSIT, 2006sirolimus eluting stentpaclitaxel eluting stentnegative
SORT OUT II, 2008sirolimus eluting stentpaclitaxel eluting stentNCT00388934negative
Cervinka, 2006sirolimus eluting stentpaclitaxel eluting stentnegative
Petronio et al, 2007sirolimus eluting stentpaclitaxel eluting stentnegative
Han, 2006sirolimus eluting stentpaclitaxel eluting stentnegative
BASKET (vs paclitaxel), 2005sirolimus eluting stentpaclitaxel eluting stentnegative
Di Lorenzo et al., 2005sirolimus eluting stentpaclitaxel eluting stentnegative
ISAR-TEST-1, 2006sirolimus eluting stentpaclitaxel eluting stentNCT00140530Risk of bias negative
ISAR-LEFT-MAIN, 2009sirolimus eluting stentpaclitaxel eluting stentNCT00133237negative
Kim, 2008sirolimus eluting stentpaclitaxel eluting stentnegative
Pan, 2007sirolimus eluting stentpaclitaxel eluting stentExploratory suggesting
DES-DIABETES, 2008sirolimus eluting stentpaclitaxel eluting stentRisk of bias suggesting
SIRTAX diabetics, 2005sirolimus eluting stentpaclitaxel eluting stentNCT00297661negative
TAxi (diabetics)sirolimus eluting stentpaclitaxel eluting stent -
REALITY (diabetics), 2006sirolimus eluting stentpaclitaxel eluting stentnegative
ISAR-DESIRE-2, 2010sirolimus eluting stentpaclitaxel eluting stentNCT00598715Risk of bias -
Wessely, 2008sirolimus eluting stentpaclitaxel eluting stentExploratory -
SIRTAX (small vessels subgroup), 2005sirolimus eluting stentpaclitaxel eluting stentsuggesting
DES-ISR ongoing sirolimus eluting stentpaclitaxel eluting stentNCT00485030 ongoing
Lipsia-Yukon-DM ongoing sirolimus eluting stentpaclitaxel eluting stentNCT00368953 ongoing
zotarolimus eluting stent
ENDEAVOR II, 2006zotarolimus eluting stentbare-metal stentLow risk of bias suggesting
RESOLUTE All comers, 2010zotarolimus eluting stenteverolimus eluting stentNCT00617084.)Risk of bias negative
TWENTE, 2012zotarolimus eluting stenteverolimus eluting stentNCT01066650 -
ENDEAVOR IV, 2009zotarolimus eluting stentpaclitaxel eluting stentNCT00217269Risk of bias suggesting
ZEST AMI (vs PES), 2009zotarolimus eluting stentpaclitaxel eluting stentNCT00422565Risk of bias negative
ZoMaxx I, 2008zotarolimus eluting stentpaclitaxel eluting stent -
ZEST (vs PES), 2009zotarolimus eluting stentpaclitaxel eluting stentNCT00418067suggesting
ZoMaxx phase 2 ongoing zotarolimus eluting stentpaclitaxel eluting stentNCT00140101 ongoing
ENDEAVOR III, 2006zotarolimus eluting stentsirolimus eluting stentNCT00217256suggesting
PROTECT, 2012zotarolimus eluting stentsirolimus eluting stentNCT00476957Risk of bias -
ZEST (vs SES), 2009zotarolimus eluting stentsirolimus eluting stentNCT00418067Risk of bias negative
SORT-OUT-3, 2010zotarolimus eluting stentsirolimus eluting stentNCT00660478Risk of bias negative
ZEST AMI (vs SES), 2009zotarolimus eluting stentsirolimus eluting stentNCT00422565negative
DIABEDES IV ongoing zotarolimus eluting stentsirolimus eluting stentNCT00552994 ongoing
PRISON III, 2007 ongoing zotarolimus eluting stentsirolimus eluting stentNCT00428454 ongoing