PCI

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultreinfarctionAll cause death

acute myocardial infarction

drug-eluting stents
DEDICATION, 2008      NCTdrug-eluting stentsbare-metal stentRisk of bias suggesting100%
PASEO, 2009   drug-eluting stentsbare-metal stent -
paclitaxel
PASSION, 2006     paclitaxel eluting stentbare-metal stentRisk of bias negative-30%
HAAMU-STENT, 2006   paclitaxel eluting stentbare-metal stentExploratory negative114%
HORIZONS-AMI Stent, 2008     paclitaxel eluting stentbare-metal stentsuggesting1%
PCI
WEST, 2006     systematic PCI (+stent)no systematic PCInegative-36%
CAPITAL AMI, 2005     systematic PCI (+stent)no systematic PCInegative-59%
GRACIA-1, 2004     systematic PCI (+stent)no systematic PCIRisk of bias negative-39%
SIAM III, 2002     systematic PCI (+stent)no systematic PCInegative-1%
PRAGUE, 2000     systematic PCI (+stent)no systematic PCInegative-51%
C-PORT, 2002     primary PCIaccelerated t-PA -
STAT, 2001     primary stentingaccelerated t-PA -
Jaksch, 1998   primary stentingballoon angioplastysuggesting-63%-40%
GRAMI (Rodriguez), 1998     primary stentingballoon angioplastynegative-100%-50%
Zwolle 5 (Suryapranata), 1998     primary stentingballoon angioplastysuggesting-79%-32%
stent-PAMI (Grines), 1999     primary stentingballoon angioplastysuggesting-61%96%
PASTA (Saito), 1999     primary stentingballoon angioplastysuggesting-100%-58%
PRISAM (Kawashima), 1999   primary stentingballoon angioplastynegative-100%
STENTIM-2 (Maillard), 2000     primary stentingballoon angioplastynegative9%+Infini%
PSSAAMI (Scheller), 2001     primary stentingballoon angioplastysuggesting-100%100%
FRESCO, 1998     primary stentingballoon angioplasty -
CADILLAC abciximab., 2002     primary stentingballoon angioplasty -
CADILLAC (no abciximab), 2002     primary stentingballoon angioplasty -
ZWOLLE 6, 2005     primary stentingballoon angioplasty -
STOPAMI 3, 2004     primary stentingballoon angioplasty -
STOPAMI 2, 2002     primary stentingimmediate thrombolysis -
senior PAMI, 2005    NCTprimary PCIThrombolysisRisk of bias suggesting
primary angioplasty
Ribichini, 1996   primary ballon angioplastyaccelerated t-PA -
Garcia, 1997     primary ballon angioplastyaccelerated t-PA -
GUSTO 2B, 1997     primary ballon angioplastyaccelerated t-PA -
DANAMI-2, 1997         primary ballon angioplastyaccelerated t-PA -
DeWood, 1989   primary ballon angioplastyduteplase -
Gibbons, 1993     primary ballon angioplastyduteplase -
O'Neill, 1986   primary ballon angioplastyintracoronary streptokinase -
Zwolle, 1994   primary ballon angioplastystreptokinasenegative -87%
Ribeiro, 1993   primary ballon angioplastystreptokinase -
Grinfeld, 1996   primary ballon angioplastystreptokinase -
Zijlstra, 1997     primary ballon angioplastystreptokinase -
Zijlstra , 1993     primary ballon angioplastystreptokinase -
Akhras, 1997   primary ballon angioplastystreptokinase -
PAMI, 1993     primary ballon angioplastyt-PA -
TRIANA, 2009    NCTprimary ballon angioplastytenecteplaseRisk of bias negative60%
PTCA
MAASTRICHT (Vermeer), 1999     primary angioplastyimmediate thrombolysisnegative
PRAGUE-1, 2000     primary angioplastyimmediate thrombolysissuggesting
AIR-PAMI, 2002     primary angioplastyimmediate thrombolysisnegative
CAPTIM, 2002     primary angioplastyimmediate thrombolysisnegative
DANAMI-2, 2003   primary angioplastyimmediate thrombolysissuggesting-69%-24%
PRAGUE-2, 2003     primary angioplastyimmediate thrombolysissuggesting
TAMI 1 pilot, 1987   immediate systematic ballon angioplastyteno immediate angioplastyExploratory suggesting
ECSG, 1988   immediate systematic ballon angioplastyteno immediate angioplastyExploratory negative-33%
TAMI-5 (Califf), 1991   immediate systematic ballon angioplastyteno immediate angioplasty -
Ellis, 1994   immediate systematic ballon angioplastyteno immediate angioplasty -
Erbel, 1989     immediate systematic ballon angioplastyteno immediate angioplasty -
MERLIN (Sutton), 2004     immediate systematic ballon angioplastyteno immediate angioplasty -
SWISS-SMASH, 1999   immediate systematic ballon angioplastyteno immediate angioplastyExploratory negative-28%
TIMI 2A, 1988   immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
Belenkie, 1991   immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
Topol, 1987   immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
REACT (rescue PCI), 2005       rescue PTCAno rescue PTCAsuggesting -76%-51%
MERLIN, 2004       rescue PTCAno rescue PTCAnegative -31%-11%
RESCUE II, 2000     rescue PTCAno rescue PTCAnegative+Infini%
RESCUE, 1994   rescue PTCAno rescue PTCAnegative-47%
Belenkie, 1992   rescue PTCAno rescue PTCARisk of bias negative-81%
SWIFT, 1991   systematic ballon angioplastyno systematic angioplastyRisk of bias negative
SIAM, 1992   systematic ballon angioplastyno systematic angioplastyExploratory negative
TIMI 2, 1989   systematic ballon angioplastyno systematic angioplastyRisk of bias negative 11%
Guerci, 1987   systematic ballon angioplastyno systematic angioplastyExploratory negative
Van den Brand, 1991   systematic ballon angioplastyno systematic angioplastyExploratory negative
TOPS, 1992   systematic ballon angioplastyno systematic angioplastyExploratory negative
TIMI II-A (defered)   systematic ballon angioplastyno systematic angioplasty -
Vermeer, 1999     systematic ballon angioplastyno systematic angioplasty -
TAMI 6, 1992   systematic ballon angioplastyno systematic angioplasty -
Barbash, 1990   systematic ballon angioplastyno systematic angioplasty -
sirolimus eluting stent
TYPHOON, 2006      NCTsirolimus eluting stentbare-metal stentsuggesting1%
SESAMI, 2007        NCTsirolimus eluting stentbare-metal stentRisk of bias suggesting-57%
MISSION, 2008   sirolimus eluting stentbare-metal stentRisk of bias suggesting-52%
Díaz de la Llera, 2007     sirolimus eluting stentbare-metal stent -
DEBATER (SES vs BMS), 2009   sirolimus eluting stentbare-metal stentsuggesting
PROSIT, 2006   sirolimus eluting stentpaclitaxel eluting stentnegative-18%
Di Lorenzo et al., 2005     sirolimus eluting stentpaclitaxel eluting stentnegative-25%
Juwana, 2009     sirolimus eluting stentpaclitaxel eluting stentnegative44%
zotarolimus eluting stent
ZEST AMI (vs PES), 2009      NCTzotarolimus eluting stentpaclitaxel eluting stentRisk of bias negative+Infini%
ZEST AMI (vs SES), 2009      NCTzotarolimus eluting stentsirolimus eluting stentnegative-24%