PCI

     

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Trial Studied trt Control trt patientstagsNCTROB Result

acute myocardial infarction

drug-eluting stents
DEDICATION, 2008drug-eluting stentsbare-metal stentNCT00192868Risk of bias suggesting
PASEO, 2009drug-eluting stentsbare-metal stent -
paclitaxel
PASSION, 2006paclitaxel eluting stentbare-metal stentISRCTN65027270Risk of bias negative
HAAMU-STENT, 2006paclitaxel eluting stentbare-metal stentExploratory negative
HORIZONS-AMI Stent, 2008paclitaxel eluting stentbare-metal stentsuggesting
PCI
WEST, 2006systematic PCI (+stent)no systematic PCInegative
CAPITAL AMI, 2005systematic PCI (+stent)no systematic PCInegative
GRACIA-1, 2004systematic PCI (+stent)no systematic PCIRisk of bias negative
SIAM III, 2002systematic PCI (+stent)no systematic PCInegative
PRAGUE, 2000systematic PCI (+stent)no systematic PCInegative
C-PORT, 2002primary PCIaccelerated t-PA -
STAT, 2001primary stentingaccelerated t-PA -
Jaksch, 1998primary stentingballoon angioplastysuggesting
GRAMI (Rodriguez), 1998primary stentingballoon angioplastynegative
Zwolle 5 (Suryapranata), 1998primary stentingballoon angioplastysuggesting
stent-PAMI (Grines), 1999primary stentingballoon angioplastysuggesting
PASTA (Saito), 1999primary stentingballoon angioplastysuggesting
PRISAM (Kawashima), 1999primary stentingballoon angioplastynegative
STENTIM-2 (Maillard), 2000primary stentingballoon angioplastynegative
PSSAAMI (Scheller), 2001primary stentingballoon angioplastysuggesting
FRESCO, 1998primary stentingballoon angioplasty -
CADILLAC abciximab., 2002primary stentingballoon angioplasty -
CADILLAC (no abciximab), 2002primary stentingballoon angioplasty -
ZWOLLE 6, 2005primary stentingballoon angioplasty -
STOPAMI 3, 2004primary stentingballoon angioplasty -
STOPAMI 2, 2002primary stentingimmediate thrombolysis -
senior PAMI, 2005primary PCIThrombolysisNCT00136929Risk of bias suggesting
primary angioplasty
Ribichini, 1996primary ballon angioplastyaccelerated t-PA -
Garcia, 1997primary ballon angioplastyaccelerated t-PA -
GUSTO 2B, 1997primary ballon angioplastyaccelerated t-PA -
DANAMI-2, 1997primary ballon angioplastyaccelerated t-PA -
DeWood, 1989primary ballon angioplastyduteplase -
Gibbons, 1993primary ballon angioplastyduteplase -
O'Neill, 1986primary ballon angioplastyintracoronary streptokinase -
Zwolle, 1994primary ballon angioplastystreptokinasenegative
Ribeiro, 1993primary ballon angioplastystreptokinase -
Grinfeld, 1996primary ballon angioplastystreptokinase -
Zijlstra, 1997primary ballon angioplastystreptokinase -
Zijlstra , 1993primary ballon angioplastystreptokinase -
Akhras, 1997primary ballon angioplastystreptokinase -
PAMI, 1993primary ballon angioplastyt-PA -
TRIANA, 2009primary ballon angioplastytenecteplaseNCT00257309Risk of bias negative
PTCA
MAASTRICHT (Vermeer), 1999primary angioplastyimmediate thrombolysisnegative
PRAGUE-1, 2000primary angioplastyimmediate thrombolysissuggesting
AIR-PAMI, 2002primary angioplastyimmediate thrombolysisnegative
CAPTIM, 2002primary angioplastyimmediate thrombolysisnegative
DANAMI-2, 2003primary angioplastyimmediate thrombolysissuggesting
PRAGUE-2, 2003primary angioplastyimmediate thrombolysissuggesting
TAMI 1 pilot, 1987immediate systematic ballon angioplastyteno immediate angioplastyExploratory suggesting
ECSG, 1988immediate systematic ballon angioplastyteno immediate angioplastyExploratory negative
TAMI-5 (Califf), 1991immediate systematic ballon angioplastyteno immediate angioplasty -
Ellis, 1994immediate systematic ballon angioplastyteno immediate angioplasty -
Erbel, 1989immediate systematic ballon angioplastyteno immediate angioplasty -
MERLIN (Sutton), 2004immediate systematic ballon angioplastyteno immediate angioplasty -
SWISS-SMASH, 1999immediate systematic ballon angioplastyteno immediate angioplastyExploratory negative
TIMI 2A, 1988immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
Belenkie, 1991immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
Topol, 1987immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
REACT (rescue PCI), 2005rescue PTCAno rescue PTCAsuggesting
MERLIN, 2004rescue PTCAno rescue PTCAnegative
RESCUE II, 2000rescue PTCAno rescue PTCAnegative
RESCUE, 1994rescue PTCAno rescue PTCAnegative
Belenkie, 1992rescue PTCAno rescue PTCARisk of bias negative
SWIFT, 1991systematic ballon angioplastyno systematic angioplastyRisk of bias negative
SIAM, 1992systematic ballon angioplastyno systematic angioplastyExploratory negative
TIMI 2, 1989systematic ballon angioplastyno systematic angioplastyRisk of bias negative
Guerci, 1987systematic ballon angioplastyno systematic angioplastyExploratory negative
Van den Brand, 1991systematic ballon angioplastyno systematic angioplastyExploratory negative
TOPS, 1992systematic ballon angioplastyno systematic angioplastyExploratory negative
TIMI II-A (defered)systematic ballon angioplastyno systematic angioplasty -
Vermeer, 1999systematic ballon angioplastyno systematic angioplasty -
TAMI 6, 1992systematic ballon angioplastyno systematic angioplasty -
Barbash, 1990systematic ballon angioplastyno systematic angioplasty -
sirolimus eluting stent
TYPHOON, 2006sirolimus eluting stentbare-metal stentNCT00232830suggesting
SESAMI, 2007sirolimus eluting stentbare-metal stentNCT00288210Risk of bias suggesting
MISSION, 2008sirolimus eluting stentbare-metal stentISRCTN62825862Risk of bias suggesting
Díaz de la Llera, 2007sirolimus eluting stentbare-metal stent -
DEBATER (SES vs BMS), 2009sirolimus eluting stentbare-metal stentsuggesting
PROSIT, 2006sirolimus eluting stentpaclitaxel eluting stentnegative
Di Lorenzo et al., 2005sirolimus eluting stentpaclitaxel eluting stentnegative
Juwana, 2009sirolimus eluting stentpaclitaxel eluting stentISRCTN90526229negative
zotarolimus eluting stent
ZEST AMI (vs PES), 2009zotarolimus eluting stentpaclitaxel eluting stentNCT00422565Risk of bias negative
ZEST AMI (vs SES), 2009zotarolimus eluting stentsirolimus eluting stentNCT00422565negative