PCI

     

Select            
Trial Studied trt Control trt patientstagsROB Trial result

acute myocardial infarction

drug-eluting stents
DEDICATION, 2008      NCTdrug-eluting stentsbare-metal stentRisk of bias suggesting
PASEO, 2009   drug-eluting stentsbare-metal stent -
paclitaxel
PASSION, 2006     paclitaxel eluting stentbare-metal stentRisk of bias negative
HAAMU-STENT, 2006   paclitaxel eluting stentbare-metal stentExploratory negative
HORIZONS-AMI Stent, 2008     paclitaxel eluting stentbare-metal stentsuggesting
PCI
WEST, 2006     systematic PCI (+stent)no systematic PCInegative
CAPITAL AMI, 2005     systematic PCI (+stent)no systematic PCInegative
GRACIA-1, 2004     systematic PCI (+stent)no systematic PCIRisk of bias negative
SIAM III, 2002     systematic PCI (+stent)no systematic PCInegative
PRAGUE, 2000     systematic PCI (+stent)no systematic PCInegative
C-PORT, 2002     primary PCIaccelerated t-PA -
STAT, 2001     primary stentingaccelerated t-PA -
Jaksch, 1998   primary stentingballoon angioplastysuggesting
GRAMI (Rodriguez), 1998     primary stentingballoon angioplastynegative
Zwolle 5 (Suryapranata), 1998     primary stentingballoon angioplastysuggesting
stent-PAMI (Grines), 1999     primary stentingballoon angioplastysuggesting
PASTA (Saito), 1999     primary stentingballoon angioplastysuggesting
PRISAM (Kawashima), 1999   primary stentingballoon angioplastynegative
STENTIM-2 (Maillard), 2000     primary stentingballoon angioplastynegative
PSSAAMI (Scheller), 2001     primary stentingballoon angioplastysuggesting
FRESCO, 1998     primary stentingballoon angioplasty -
CADILLAC abciximab., 2002     primary stentingballoon angioplasty -
CADILLAC (no abciximab), 2002     primary stentingballoon angioplasty -
ZWOLLE 6, 2005     primary stentingballoon angioplasty -
STOPAMI 3, 2004     primary stentingballoon angioplasty -
STOPAMI 2, 2002     primary stentingimmediate thrombolysis -
senior PAMI, 2005    NCTprimary PCIThrombolysisRisk of bias suggesting
primary angioplasty
Ribichini, 1996   primary ballon angioplastyaccelerated t-PA -
Garcia, 1997     primary ballon angioplastyaccelerated t-PA -
GUSTO 2B, 1997     primary ballon angioplastyaccelerated t-PA -
DANAMI-2, 1997         primary ballon angioplastyaccelerated t-PA -
DeWood, 1989   primary ballon angioplastyduteplase -
Gibbons, 1993     primary ballon angioplastyduteplase -
O'Neill, 1986   primary ballon angioplastyintracoronary streptokinase -
Zwolle, 1994   primary ballon angioplastystreptokinasenegative
Ribeiro, 1993   primary ballon angioplastystreptokinase -
Grinfeld, 1996   primary ballon angioplastystreptokinase -
Zijlstra, 1997     primary ballon angioplastystreptokinase -
Zijlstra , 1993     primary ballon angioplastystreptokinase -
Akhras, 1997   primary ballon angioplastystreptokinase -
PAMI, 1993     primary ballon angioplastyt-PA -
TRIANA, 2009    NCTprimary ballon angioplastytenecteplaseRisk of bias negative
PTCA
MAASTRICHT (Vermeer), 1999     primary angioplastyimmediate thrombolysisnegative
PRAGUE-1, 2000     primary angioplastyimmediate thrombolysissuggesting
AIR-PAMI, 2002     primary angioplastyimmediate thrombolysisnegative
CAPTIM, 2002     primary angioplastyimmediate thrombolysisnegative
DANAMI-2, 2003   primary angioplastyimmediate thrombolysissuggesting
PRAGUE-2, 2003     primary angioplastyimmediate thrombolysissuggesting
TAMI 1 pilot, 1987   immediate systematic ballon angioplastyteno immediate angioplastyExploratory suggesting
ECSG, 1988   immediate systematic ballon angioplastyteno immediate angioplastyExploratory negative
TAMI-5 (Califf), 1991   immediate systematic ballon angioplastyteno immediate angioplasty -
Ellis, 1994   immediate systematic ballon angioplastyteno immediate angioplasty -
Erbel, 1989     immediate systematic ballon angioplastyteno immediate angioplasty -
MERLIN (Sutton), 2004     immediate systematic ballon angioplastyteno immediate angioplasty -
SWISS-SMASH, 1999   immediate systematic ballon angioplastyteno immediate angioplastyExploratory negative
TIMI 2A, 1988   immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
Belenkie, 1991   immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
Topol, 1987   immediate systematic ballon angioplastyteno immediate angioplastyExploratory -
REACT (rescue PCI), 2005       rescue PTCAno rescue PTCAsuggesting
MERLIN, 2004       rescue PTCAno rescue PTCAnegative
RESCUE II, 2000     rescue PTCAno rescue PTCAnegative
RESCUE, 1994   rescue PTCAno rescue PTCAnegative
Belenkie, 1992   rescue PTCAno rescue PTCARisk of bias negative
SWIFT, 1991   systematic ballon angioplastyno systematic angioplastyRisk of bias negative
SIAM, 1992   systematic ballon angioplastyno systematic angioplastyExploratory negative
TIMI 2, 1989   systematic ballon angioplastyno systematic angioplastyRisk of bias negative
Guerci, 1987   systematic ballon angioplastyno systematic angioplastyExploratory negative
Van den Brand, 1991   systematic ballon angioplastyno systematic angioplastyExploratory negative
TOPS, 1992   systematic ballon angioplastyno systematic angioplastyExploratory negative
TIMI II-A (defered)   systematic ballon angioplastyno systematic angioplasty -
Vermeer, 1999     systematic ballon angioplastyno systematic angioplasty -
TAMI 6, 1992   systematic ballon angioplastyno systematic angioplasty -
Barbash, 1990   systematic ballon angioplastyno systematic angioplasty -
sirolimus eluting stent
TYPHOON, 2006      NCTsirolimus eluting stentbare-metal stentsuggesting
SESAMI, 2007        NCTsirolimus eluting stentbare-metal stentRisk of bias suggesting
MISSION, 2008   sirolimus eluting stentbare-metal stentRisk of bias suggesting
Díaz de la Llera, 2007     sirolimus eluting stentbare-metal stent -
DEBATER (SES vs BMS), 2009   sirolimus eluting stentbare-metal stentsuggesting
PROSIT, 2006   sirolimus eluting stentpaclitaxel eluting stentnegative
Di Lorenzo et al., 2005     sirolimus eluting stentpaclitaxel eluting stentnegative
Juwana, 2009     sirolimus eluting stentpaclitaxel eluting stentnegative
zotarolimus eluting stent
ZEST AMI (vs PES), 2009      NCTzotarolimus eluting stentpaclitaxel eluting stentRisk of bias negative
ZEST AMI (vs SES), 2009      NCTzotarolimus eluting stentsirolimus eluting stentnegative