anti-anginal drugs

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Trial Studied trt Control trt patientstagsNCTROB Result

acute coronary syndrome

ranolazine
MERLIN TIMI 36, 2007ranolazine placeboNCT00099788suggesting

coronary artery disease

nicorandil
Nishimura, 2009nicorandilcontrolRisk of bias -
ranolazine
MARIZA, 2004ranolazine 1000mgplacebo -
RAN080, 2005ranolazine 1000mgplacebo -
CARISA 1000mg, 2004ranolazine 1000mgplacebo (on top standard treatment)negative
ERICA, 2006ranolazine 1000mg + amlodipineplacebo + amlodipineNCT00091429Low risk of bias -

percutaneous coronary intervention

nicorandil
Nishimura, 2009nicorandilcontrolRisk of bias -

stable angina

ranolazine
MARIZA, 2004ranolazine 1000mgplacebo -
RAN080, 2005ranolazine 1000mgplacebo -
CARISA 1000mg, 2004ranolazine 1000mgplacebo (on top standard treatment)negative
ERICA, 2006ranolazine 1000mg + amlodipineplacebo + amlodipineNCT00091429Low risk of bias -