angiotensin-Converting Enzyme Inhibitors

Benazepril - Captopril - Enalapril - Fosinopril - Lisinopril - Perindopril - Quinapril - Ramipril - Trandolapril - Various ACEI - Zofenopril      

Select            
Trial Studied trt Control trt patientstagsROB Trial result

acute myocardial infarction

captopril
ISIS-4, 1995   captoprilplaceboLow risk of bias -
CCS-1, 1995   captoprilplaceboLow risk of bias -
French, 1999     captoprilplaceboLow risk of bias -
CATS, 1996     captoprilplaceboLow risk of bias -
ECCE, 1997   captoprilplaceboLow risk of bias -
Sharpe, 1991     captoprilplaceboLow risk of bias -
Ray, 1993     captoprilplaceboLow risk of bias -
Nabel, 1991   captoprilplaceboLow risk of bias -
Bussmann, 1992   captoprilplaceboLow risk of bias -
Di Pasquale, 1994   captoprilplaceboLow risk of bias -
Di Pasquale, 1997   captoprilplaceboLow risk of bias -
Galcera, 1993   captoprilplaceboLow risk of bias -
Hargreaves, 1992   captoprilplaceboLow risk of bias -
SAVE, 1992   captoprilplaceboLow risk of bias -
Pfeffer, 1988   captoprilplaceboLow risk of bias -
Sogaard, 1994   captoprilplaceboLow risk of bias -
Sharpe, 1988     captoprilplaceboLow risk of bias -
Mortarino, 1990   captoprilplaceboLow risk of bias -
PRACTICAL (captopril), 1994   captopril or enalaprilplaceboLow risk of bias -
enalapril
CONSENSUS 2, 1992   enalaprilplaceboLow risk of bias -
Schulman, 1995     enalaprilplaceboLow risk of bias -
fosinopril
FAMIS, 1998     fosinoprilplaceboLow risk of bias -
lisinopril
GISSI 3, 1994   lisinoprilplaceboRisk of bias -
ramipril
Wagner, 2002   ramiprilplaceboLow risk of bias -
AIRE, 1993   ramiprilplaceboLow risk of bias -
trandolapril
TRACE, 1995     trandolaprilplaceboLow risk of bias -
zofenopril
SMILE, 1995     zofenoprilplaceboLow risk of bias suggesting

heart failure

benazepril
McGany, 1991   benazeprilcontrolnegative
Colfer, 1992   benazeprilplaceboLow risk of bias negative
captopril
Magnani, 1986   captoprilplaceboLow risk of bias -
Bussmann, 1987   captoprilplaceboLow risk of bias negative
Captopril Digoxin Multicenter Research Group, 1988   captoprilplaceboLow risk of bias negative
Barabino, 1991   captoprilplaceboLow risk of bias suggesting
Munich MHFT (Kleber), 1992   captoprilplaceboLow risk of bias negative
Magnani, 1990   captoprilplaceboLow risk of bias -
CMRG, 1983   captoprilplaceboLow risk of bias -
Cilazapril-Captopril Multi-centre Group (capt vs pbo), 1995   captoprilplaceboLow risk of bias -
SAVE, 1992   captoprilplaceboLow risk of bias -
Pfeffer, 1988   captoprilplaceboLow risk of bias -
Sogaard, 1994   captoprilplaceboLow risk of bias -
Sharpe, 1988     captoprilplaceboLow risk of bias -
Mortarino, 1990   captoprilplaceboLow risk of bias -
packer, 1986   captoprilenalaprilExploratory -
cilazapril
Drexler, 1989   cilazaprilplaceboLow risk of bias negative
Dosseger, 1993   cilazaprilplaceboLow risk of bias -
Cilazapril-Captopril Multi-centre Group, 1995   cilazaprilplaceboLow risk of bias -
Cilazapril-Captopril Multi-centre Group (cila vs capt), 1995   cilazaprilcaptoprilLow risk of bias -
enalapril
Rucinska-b (enalapril), 1991   enalaprilcontrolnegative
Enalapril CHF investigators, 1987   enalaprilcontrolnegative
Rucinska-a (enalapril), 1991   enalaprilcontrolnegative
SOLVD treatment, 1991    NCTenalaprilplaceboLow risk of bias suggesting
SOLVD prevention, 1992    NCTenalaprilplaceboLow risk of bias -
Cleland, 1985   enalaprilplaceboLow risk of bias negative
CONSENSUS, 1987   enalaprilplaceboLow risk of bias negative
Dickstein, 1991   enalaprilplaceboLow risk of bias negative
Sharpe, 1984   enalaprilplaceboLow risk of bias -
McGrath, 1985     enalaprilplaceboLow risk of bias -
Chrysant, 1985   enalaprilplaceboLow risk of bias -
CASSIS (enalapril), 1995   enalaprilplaceboLow risk of bias -
NETWORK (2.5 bid vs 10 bid), 1998   enalaprilenalaprilLow risk of bias -
NETWORK (5 bid vs 10 bid), 1998   enalaprilenalaprilLow risk of bias -
V-HeFT II, 1991   enalaprilhydralazine+ISDNLow risk of bias -
fosinopril
Brown, 1995     fosinoprilplaceboLow risk of bias -
FEST (Erhardt), 1996     fosinoprilplaceboLow risk of bias -
lisinopril
Zwehl, 1990   lisinoprilcontrolnegative
Giles, 1990   lisinoprilcontrolnegative
Rucinska-c (lisinopril), 1000   lisinoprilcontrolnegative
Gilbert, 1993   lisinoprilplaceboLow risk of bias negative
International Study Group (Lewis), 1989   lisinoprilplaceboLow risk of bias -
ATLAS, 1999   lisinoprillisinoprilLow risk of bias -
perindopril
Lechat, 1993   perindoprilplaceboLow risk of bias negative
PEP CHF, 2006   perindoprilplaceboLow risk of bias negative
quinapril
Uprichard-a, 1994   controlnegative
Uprichard-b, 1994   controlnegative
Uprichard-c, 1994   controlnegative
Riegger, 1990   placeboLow risk of bias negative
Northridge, 1991     placeboLow risk of bias negative
Rieger, 1991   placeboLow risk of bias negative
Nussberger, 1994   placeboLow risk of bias -
Quinapril Heart Failure Trial Investigators, 1993   placeboLow risk of bias -
ramipril
Swedberg, 1991   ramiprilcontrolnegative
Maass-a, 1991   ramiprilplacebonegative
Gordon, 1991     ramiprilplaceboLow risk of bias suggesting
Maass-b, 1991   ramiprilplaceboLow risk of bias negative
Maass-c, 1991     ramiprilplaceboLow risk of bias negative
Lemarie, 1992     ramiprilplaceboLow risk of bias negative
Gundersen, 1994     ramiprilplaceboLow risk of bias -
AIRE, 1993   ramiprilplaceboLow risk of bias -
trandolapril
Hampton, 1998     trandolaprilplaceboLow risk of bias -
TRACE, 1995     trandolaprilplaceboLow risk of bias -

patients at high risk for cardiovascular events

enalapril
CAMELOT (enalapril), 2004     enalaprilplaceboLow risk of bias negative
perindopril
EUROPA, 2003     perindoprilplaceboLow risk of bias suggesting
quinapril
QUIET, 2001     quinaprilplaceboLow risk of bias negative
ramipril
HOPE, 2000     ramiprilplaceboLow risk of bias suggesting
ONTARGET (association vs ramipril), 2008    NCTtelmisartan + ramiprilramiprilLow risk of bias negative
ONTARGET (association vs telmisartan), 2008    NCTtelmisartan + ramipriltelmisartanLow risk of bias suggesting
trandolapril
PEACE, 2004      NCTtrandolaprilplaceboLow risk of bias suggesting