niacin

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultCoronary eventcardiovascular events

cardiovascular prevention

niacin
VA drugs, 1968   niacincontrolLow risk of bias negative
UCSF SCOR, 1990     niacin+colestipolcontrolExploratory negative-100%-100%
Carlson (Stockholm), 1977   clofibtate+niacinplacebosecondary preventionRisk of bias suggesting-29%
CLAS, 1987   colestipol-niacinplacebosecondary preventionExploratory negative
CDP niacin, 1975   niacinplaceboLow risk of bias suggesting-15%
FATS, 1990     niacin+colestipolplaceboLow risk of bias suggesting-78%
AIM-HIGH, 2011      NCTniacinplacebo (on top statin)Low risk of bias negative4%2%
HPS 2-Thrive      NCTniacinplacebo (on top statin)Low risk of bias negative-4%-4%
Oxford Niaspan Study, 2009    NCTniacinplacebo (on top statin)Exploratory -
ARBITER 2, 2009   niacinplacebo (on top statin)Exploratory negative-8%-61%
HATS, 2001   niacinplacebo (on top statin)Low risk of bias negative-80%-60%
ARBITER 6-HALTS (niacin vs ezetimibe), 2009        NCTniacinezetimibeExploratory suggesting -79%2849%
Guyton, 2008     niacin+ezetimibesimvastatin+ezetimibeLow risk of bias negative -60%2153%