niacin

     

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Trial Studied trt Control trt patientstagsNCTROB Result

cardiovascular prevention

niacin
VA drugs, 1968niacincontrolLow risk of bias negative
UCSF SCOR, 1990niacin+colestipolcontrolExploratory negative
Carlson (Stockholm), 1977clofibtate+niacinplacebosecondary preventionRisk of bias suggesting
CLAS, 1987colestipol-niacinplacebosecondary preventionExploratory negative
CDP niacin, 1975niacinplaceboLow risk of bias suggesting
FATS, 1990niacin+colestipolplacebosuggesting
AIM-HIGH, 2011niacinplacebo (on top statin)NCT00120289Low risk of bias negative
HPS 2-Thriveniacinplacebo (on top statin)NCT00461630Low risk of bias negative
Oxford Niaspan Study, 2009niacinplacebo (on top statin)NCT00232531Exploratory -
ARBITER 2, 2009niacinplacebo (on top statin)Exploratory negative
HATS, 2001niacinplacebo (on top statin)Risk of bias negative
ARBITER 6-HALTS (niacin vs ezetimibe), 2009niacinezetimibeNCT00397657Exploratory suggesting
Guyton, 2008niacin+ezetimibesimvastatin+ezetimibeExploratory negative