New P2Y12 Inhibitors

     

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Trial Studied trt Control trt patientstagsNCTROB Result

acute coronary syndrome

cangrelor
CHAMPION-PCI, 2009cangrelor up frontclopidogrel up frontNCT00305162Low risk of bias negative
CHAMPION-PLATFORM, 2009cangrelor up frontdelayed clopidogrelNCT00385138negative
elinogrel
ERASE-MI, 2009elinogrelplaceboExploratory negative
prasugrel
JUMBO-TIMI 26, 2005prasugrelclopidogrelExploratory negative
TRITON-TIMI 38, 2007prasugrelclopidogrelNCT00097591Low risk of bias suggesting
ticagrelor
PLATO, 2009ticagrelorclopidogrelNCT00391872Low risk of bias suggesting
DISPERSE-2 (90mg), 2007ticagrelorclopidogrelExploratory negative