pentasaccharide

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultMajor bleedingVenous thromboembolism

thrombosis prevention

fondaparinux
DRI4757   fondaparinuxplaceboknee surgeryLow risk of bias -
ARTEMIS (Cohen), 2006     fondaparinuxplacebomedical patientsLow risk of bias negative-3%
APOLLO (Turpie), 2007     fondaparinuxplacebo (on top intermittent pneumatic comp.)abdominal surgeryLow risk of bias suggesting 924%-69%
PENTAMAKS (Bauer), 2001     fondaparinuxenoxaparinknee surgeryLow risk of bias suggesting 1000%-55%
PENTHIFRA (Eriksson), 2001     fondaparinuxenoxaparinhip surgeryLow risk of bias suggesting-4%-56%
PENTATHLON (Turpie), 2002     fondaparinuxenoxaparinhip surgeryLow risk of bias suggesting 82%-26%
EPHESUS (Lassen), 2002     fondaparinuxenoxaparinhip surgeryLow risk of bias suggesting51%-56%
Turpie, 2001     fondaparinuxenoxaparinhip surgeryLow risk of bias -
L8541   fondaparinuxenoxaparinorthopaedic surgeryLow risk of bias negative-8%
L8635   fondaparinuxenoxaparinknee surgeryExploratory negative-22%
PEGASUS, 2005     fondaparinuxenoxaparinabdominal surgeryLow risk of bias negative39%-25%