obesity and overweight  

     

Select
Display
Trial Studied trt Control trt patientstagsNCTROB Result

All mechanism

not classified
Breum, 1995Fluoxetineplacebo -
Connolly, 1995Fluoxetineplacebo -
Darga, 1991Fluoxetineplacebo -
Goldstein, 1994Fluoxetineplacebo -
Gray, 1992Fluoxetineplacebo -
Marcus, 1990Fluoxetineplacebo -
Mendoza Espejo, 1995Fluoxetineplacebo -
Michelson 50wk, 1999Fluoxetineplacebo -
O’Kane, 1994Fluoxetineplacebo -
APD356-004, 2009lorcaserinplacebo -
Astruptesofensineplacebo -
Bupropion
Anderson, 2002BupropionplaceboLow risk of bias -
Croft, 2002Bupropionplacebo -
Jain, 2002BupropionplaceboLow risk of bias -
liraglutide
Astrup (NN8022-1807 ), 2009liraglutideplaceboNCT00422058Low risk of bias -
lorcaserin
BLOSSOM (10mg bid), 2009lorcaserinplaceboNCT00603902Low risk of bias -
BLOOM, 2010lorcaserinplaceboNCT00395135Low risk of bias -
BLOOM-DM (10mg bid)lorcaserinplaceboNCT00603291Low risk of bias -
orlistat
Bakris, 2002OrlistatplaceboLow risk of bias -
Broom, 2002OrlistatplaceboLow risk of bias -
Broom,, 2001Orlistatplacebo -
Davidson, 1999OrlistatplaceboLow risk of bias -
Deerochanawong,, 2001Orlistatplacebo -
Derosa, 2003OrlistatplaceboLow risk of bias -
Gotfredsen, 2001Orlistatplacebo -
Halpern, 2003OrlistatplaceboLow risk of bias -
Hanefeld, 2002Orlistatplacebo -
Hauptman, 2000OrlistatplaceboLow risk of bias -
Hill, 1999OrlistatplaceboLow risk of bias -
Hollander, 1998Orlistatplacebo -
Karhunen, 2000Orlistatplacebo -
Kelley, 2002OrlistatplaceboLow risk of bias -
Krempf, 2005Orlistatplacebo -
Lindgarde, 2000Orlistatplacebo -
Lucas, 2003Orlistatplacebo -
Micic, 1999OrlistatplaceboLow risk of bias -
Miles, 2002OrlistatplaceboLow risk of bias -
Muls, 2001OrlistatplaceboLow risk of bias -
Naumov, 2002Orlistatplacebo -
Reaven, 2001Orlistatplacebo -
Rissanen, 2001OrlistatplaceboLow risk of bias -
Rosenfalck, 2002Orlistatplacebo -
Rossner, 2000OrlistatplaceboLow risk of bias -
Shi Yi, 2001Orlistatplacebo -
Sjostrom, 1998OrlistatplaceboLow risk of bias -
Vidgren, 1999Orlistatplacebo -
phentermine and topiramate
CONQUER (high-dose) (OB 303)PHEN/TPM high doseplaceboNCT00553787 -
OB 302 (high-dose)PHEN/TPM high doseplacebo -
OB 301 (high-dose)PHEN/TPM high doseplacebo -
OB 302 (low-dose)PHEN/TPM low-doseplacebo -
OB 301 (mid-dose)PHEN/TPM mid-doseplacebo -
CONQUER (mid-dose) (OB 303)PHEN/TPM mid-doseplaceboNCT00553787 -
Sibutramine
McMahon, 2000Sibutramineplacebo -
McMahon, 2002Sibutramineplacebo -
Smith, 2001Sibutramineplacebo -
SCOUT, 2010sibutramineplaceboNCT00234832Low risk of bias -
topiramate
Bray, 2003Topiramateplacebo -
Caterson, 2003Topiramateplacebo -
Pud’homme, 2003Topiramateplacebo -
Rissanen, 2003Topiramateplacebo -
Stenlof, 2003Topiramateplacebo -
Tonstad, 2003Topiramateplacebo -