peripheral vascular diseases

     

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Display
Trial Studied trt Control trt patientstagsNCTROB Result

anticoagulant

not classified
Kretschmer, 1992phenprocoumoncontrôle -
VOYAGER PAD ongoing rivaroxabanplaceboNCT02504216 ongoing
warfarin
Johnson, 2002warfarincontrôle -
Sarac, 1998warfarincontrôle -

antioxydants

not classified
ADMIT ongoing antioxydant associationplaceboNCT00000539 ongoing
POPADAD (antioxydant), 2008combinationplaceboISRCTN53295293Low risk of bias negative
vitamin e
Livingstone, 1958placebo -
Hamilton, 1953placebo -

antiplatelets drug

not classified
Brittenden J ongoing ongoing
Brittenden J (2) ongoing ongoing
Fowkes FGR ongoing ongoing
McCollum CN ongoing ongoing
aspirin
Schoop, 1983aspirinplacebo -
Hess, 1985aspirinplacebo -
Munich A, 1975aspirinplacebo -
Munich B, 1975aspirinplacebo -
CLIPS, 2007aspirinplaceboLow risk of bias suggesting
clopidogrel
CAPRIE, 1996clopidogrelaspirin -
dipyridamol
Hess (2), 1985aspirin + dipyridamolplacebo -
Schoop (2), 1983aspirin + dipyridamolplacebo -
VA study, 1986aspirin + dipyridamolplacebo -
ketanserine
PACK, 1996ketanserineplacebo -
Walden, 1991ketanserineplacebo -
Thulesius, 1987ketanserineplacebo -
picotamide
ADEP, 1993picotamideplacebo -
Neirotti, 1994picotamideplacebo -
Coto, 1989picotamideplacebo -
suloctidil
Adriaensen, 1976suloctidilplacebo -
Verhaeghe, 1981suloctidilplacebo -
Jones, 1982suloctidilplacebo -
Holm, 1984suloctidilplacebo -
ticagrelor
EUCLID, 2016ticagrelorclopidogrelNCT01732822 -
ticlopidine
EMATAP, 1993ticlopidineplacebo -
Katsumara, 1982ticlopidineplacebo -
Aukland, 1982ticlopidineplacebo -
Stiegler, 1984ticlopidineplacebo -
Ellis, 1986ticlopidineplacebo -
Cloarec, 1986ticlopidineplacebo -
Arcan, 1988ticlopidineplacebo -
Balsano, 1989ticlopidineplacebo -
STIMS, 1990ticlopidineplacebo -
Hurlow, 1980ticlopidineplacebo -
Krause, 1980ticlopidineplacebo -
various
CRAMPS, 2000cloricromeneplacebo -

antithrombotics

not classified
WAVE ongoing ongoing
CASPAR ongoing ongoing
Goldman, 1984contrôle -
Clyne, 1987contrôle -
Donaldson, 1985contrôle -
Green, 1982contrôle -
Kohler , 1984contrôle -
McCollum, 1991contrôle -
Kretschmer, 1992phenprocoumoncontrôle -
Calabro, 1993LMWHplacebo -
Mannarino, 1991LMWHplacebo -
De Smit, 1987phenprocoumonplacebo -
VOYAGER PAD ongoing rivaroxabanplaceboNCT02504216 ongoing
Edmondson, 1994HBPM -
acenocoumarol
APIC, 1989acenocoumarolplacebo -
aspirin
Lassila R, 1991aspirincontrôle -
CLIPS, 2007aspirinplaceboLow risk of bias suggesting
BOA, 2000aspirin -
clopidogrel
AFFIRM ongoing clopidogrel ongoing
ticlopidine
Becquemin, 1997ticlopidinecontrôle -
UFH
Antonicelli, 1999HNFplacebo -
Tesi, 1989HNFplacebo -
warfarin
Johnson, 2002warfarincontrôle -
Sarac, 1998warfarincontrôle -

cell-based therapies

not classified
RAVE (Rajagopalan), 2003AdVEGF121placebo -
DELTA (Grossman), 2007Del-1placebo -
Kusumanto, 2006phVEGF165placebo -
TRAFFIC (Lederman), 2002rFGF-2placebo -
Makinen, 2002VEGF geneplacebo -

cholesterol lowering intervention

not classified
Amburgey CF ongoing Peripheral Arterial Disease ongoing
atorvastatin
Mohler III, 2003atorvastatinplaceboPeripheral Arterial DiseaseExploratory -
bezafibrate
LEADER trial, 2000bezafibrateplaceboPeripheral Arterial DiseaseLow risk of bias -
niacin
CLAS, 1987colestipol-niacinplaceboPeripheral Arterial DiseaseExploratory -
probucol
PQRST, 1994probucolplaceboPeripheral Arterial DiseaseExploratory -
simvastatin
HPS (sub group), 2002simvastatinplaceboPeripheral Arterial DiseaseLow risk of bias -
Mondillo, 2003simvastatinplaceboPeripheral Arterial DiseaseExploratory -
Aronow , 2003simvastatinplaceboPeripheral Arterial DiseaseExploratory -

Exercise Therapy

Exercise Therapy
Gelin, 2001Exercise TherapyControl -
Mannarino E, 1991Exercise TherapyControl -
Dahllof AG, 1974Exercise TherapyControl -
Hiatt WR, 1990Exercise TherapyControl -
Hiatt WR, 1994Exercise TherapyControl -
Larsen OA, 1966Exercise TherapyControl -
Tisi PV, 1997Exercise TherapyControl -
Holm J, 1973Exercise TherapyControl -
Fowler, 2002Exercise TherapyControl -
Gardner, 2001Exercise TherapyControl -
Lear PA ongoing Exercise TherapyControl ongoing
Pockley G ongoing Exercise TherapyControl ongoing
Stewart A ongoing Exercise TherapyControl ongoing
McCloskey B ongoing Exercise TherapyControl ongoing
Jayatunga AP ongoing Exercise TherapyControl ongoing

vasodilators therapy

not classified
Farquhar JW ongoing ongoing
Cornu C ongoing ongoing
Vowden P ongoing ongoing
Barnes RW, 1977sympathectomiecontrôle -
Satiani B, 1982sympathectomiecontrôle -
buflomedil
LIMB, 2008buflomedilplaceboLow risk of bias suggesting
Diamantopoulos, 2001buflomédilplacebo -
cilostazol
Beebe, 1999cilostazolplacebo -
Dawson, 1998cilostazolplacebo -
Money, 1998cilostazolplacebo -
Strandness, 2002cilostazolplacebo -
Dawson (cilostazol), 2000cilostazolplacebo -
Elam, 1998cilostazolplacebo -
Otsuka 21-95-201cilostazolplacebo -
ginko biloba
Bauer, 1984ginko bilobaplacebo -
Peters, 1998ginko bilobaplacebo -
naftidrofuryl
Meehan, 1982naftidrofuryl IVcontrol -
NIQOL germany, 1999Naftidrofurylplacebo -
Clyne, 1980naftidrofurylplacebo -
NIQOL belgium, 2001naftidrofurylplacebo -
NCIS, 2001naftidrofurylplacebo -
Testart, 1994naftidrofuryl IVplacebo -
D'Hooge D, 2001naftidrofuryl IVplacebo -
Negus, 1987naftidrofuryl IVprostacyclin -
pentoxifylline
Dawson (pentoxifylline), 2000pentoxifyllineplacebo -
APIC, 1989pentoxifyllineplacebo -
Donaldson, 1984pentoxifyllineplacebo -
Porter, 1982pentoxifyllineplacebo -
Belcaro, 2002pentoxifyllineplacebo -