superficial thrombophlebitis

systematic review meta-analysis network meta-analysis

Select antithrombotics superficial thrombophlebitis of the leg       acetaminantivitamins KdefibrotidedesminEnzyme therapyEssavenEtofenakExhirudFixed-dose LMWHfondaparinuxHeparansulphateheparin SCheparin spraygelHigh-dose UFHNimesulideNSAIDsProphylactic LMWHProphylactic UFHsurgeryTherapeutic LMWHthrombectomyTopical methylthioadenosineVasotoninWeight-adjusted LMWH candesartancoumadindefibrotideDiclofenacenoxaparinfondaparinuxheparinnadroparinNimesulideUFH vs antithromboticsvs placebo or control      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results NCT results	Deep vein thrombosis Extension and/or recurrence of SVT Heparin-induced thrombocytopenia Major bleedingPain disappearance Venous thromboembolismVenous thromboembolism end of treatment
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result
antithrombotics
not classified
Holzgreve, 1989	Etofenak	diclofenac				-
Nusser, 1991	Oral acetamin	diclofenac				-
Belcaro, 1989	thrombectomy plus ECB	ECB				-
Katzenschlager (LMWH vs hep spraygel), 2003	LMWH	heparin spraygel				-
Gorski (LMWH vs hep spraygel), 2005	LMWH	heparin spraygel				-
Belcaro (complete stripping vs low dose hep), 1999	complete stripping	low dose heparin				-
Belcaro (ligation vs low dose hep), 1999	ligation	low dose heparin				-
Belcaro (LMWH vs low dose hep), 1999	LMWH	low dose heparin				-
STENOX (enox fixed dose vs NSAIDS), 2003	Fixed-dose LMWH	NSAIDs				-
STENOX (prophylactic LMWH vs NSAIDs), 2003	Prophylactic LMWH	NSAIDs				-
Incandela, 2001	Essaven	placebo				-
De Sanctis, 2001	Essaven	placebo				-
Nocker (exhirud), 1991	Exhirud ointment	placebo				-
Anonymous, 1970	Indomethacin	placebo			Low risk of bias	-
Archer, 1977	Oxyphenbutazone	placebo				-
STENOX (tenoxicam vs PBO), 2003	tenoxicam	placebo				-
Pinto, 1992	Topical methylthioadenosine	placebo				-
Kuhlwein, 1985	Vasotonin forte	placebo				-
Koshkin, 2001	Wobenzym	placebo				-
Marshall, 2001	Wobenzym	placebo				-
Lozano, 2003	Therapeutic LMWH	saphenofemoral disconnection				-
Messa, 1997	Heparansulphate	sulodexide				-
candesartan
Andreozzi (200 vs 100), 1996	desmin 200	desmin 100				-
Andreozzi (desmin SC vs 100), 1996	desmin SC	desmin 100				-
coumadin
Belcaro (coumadin vs low dose hep), 1999	coumadin	low dose heparin				-
defibrotide
Belcaro, 1990	defibrotide	low dose heparin				-
Diclofenac
Nocker (diclofenac), 1991	Diclofenac	placebo				-
enoxaparin
Stenox (enoxaparin 40mg), 2003	enoxaparin	placebo				-
STENOX (enoxaparin 1.5mg/hg), 2003	enoxaparin	placebo				-
fondaparinux
CALISTO, 2010    NCT	fondaparinux	placebo			Low risk of bias	suggesting
heparin
Belcaro (hep vs defibrotide), 1990	heparin					-
Gorski, 2005	heparin spraygel	clexane				-
Katzenschlager, 2003	liposomal heparin-spraygel	enoxaparin				-
Marchiori, 2002	heparin	low dose UFH				-
Belcaro (hep vs no hep), 1989	heparin	no treatment				-
nadroparin
Vesalio, 2005	nadroparin fixed-dose	nadroparin weight-adjusted				-
Titon (nadroparin 0.6ml vs naproxen), 1994	nadroparin	naproxene				-
Titon (nadroparin 61.5 IU anti-Xa/kg vs naproxen), 1994	nadroparin	naproxene				-
Nimesulide
Ferrari, 1992	Nimesulide	diclofenac				-
UFH
Belcaro (prophylactic UFH vs no), 1999	Prophylactic UFH	no treatment				-