familial hypercholesterolemia

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultCardiovascular deathAll cause death

cholesterol lowering intervention

ezetimibe
Enhance, 2008   ezetimibeplacebo (on top statins)Low risk of bias -
pactimibe
CAPTIVATE, 2009      NCTpactimibeplaceboLow risk of bias -
torcetrapib
RADIANCE 1, 2007      NCTtorcetrapibplaceboExploratory negative-100%-100%