impaired fasting glucose

     

Select            
Trial Studied trt Control trt patientstagsROB Trial resultDiabetes All cause death

prevention

not classified
US-DDP (lifestyle) (Knowler), 2002     lifestyle modificationcontrolRisk of bias -
STOP-NIDDM (Chiasson), 2002       errorplaceboLow risk of bias negative-25%
GRACE - ORIGIN (n-3 fatty acid)   n-3 fatty acid supplementplaceboLow risk of bias -
glargine
GRACE - ORIGIN (glargine), 2012   insulin glargineplaceboRisk of bias -
metformin
US-DPP (metformin) (Knowler), 2002     metforminplaceboLow risk of bias negative-31%
CANOE, 2010      NCTrosiglitazone and metforminplaceboLow risk of bias suggesting-75%
nateglinide
NAVIGATOR nateglinide, 2010    NCTnateglinideplaceboLow risk of bias negative 6%0%
ramipril
DREAM ramipril, 2006        NCTramiprilplaceboLow risk of bias negative -7%-2%
rosiglitazone
DREAM rosiglitazone, 2006      NCTrosiglitazoneplaceboLow risk of bias suggesting -53%1%
valsartan
NAVIGATOR valsartan, 2010        NCTvalsartanplaceboLow risk of bias suggesting-10%-9%
voglibose
Voglibose Ph-3, 2009       vogliboseplaceboLow risk of bias suggesting-54%