aortic stenosis

     

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Trial Studied trt Control trt patientstagsNCTROB Result

cholesterol lowering intervention

atorvastatin
SALTIRE, 2005atorvastatinplaceboaortic stenosisExploratory negative
rosuvastatin
ASTRONOMER, 2010rosuvastatinplaceboaortic stenosisISRCTN 32424163 -
simvastatin
SEAS, 2008ezetimibe+simvastatinplaceboaortic stenosisNCT00092677Low risk of bias negative

transcatheter aortic-valve implantation (TAVI)

TAVI
PARTNER, 2010transcatheter aortic valve implantationstandard therapyNCT00530894Risk of bias suggesting
PARTNER cohort A, 2011transcatheter aortic valve implantationsurgical valve replacementNCT00530894 -
CoreValve US pivotal trial ongoing transcatheter aortic valve implantationsurgical valve replacementNCT01240902 ongoing