miscellaneous

     

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Trial Studied trt Control trt patientstagsNCTROB Result

angiotensin-receptor blockers

not classified
Suzuki, 2008ARBscontrolRisk of bias negative
Ruilope, 2010LCZ696placeboExploratory -
IDNT (irbesartan vs amlodipine), 2001irbesartanamlodipineLow risk of bias negative
VALUE, 2004valsartanamlodipineNCT00129233Low risk of bias suggesting
DETAIL, 2004telmisartanenalaprilExploratory negative
OSCAR, 2011olmesartan 40 mgolmesartan 20 mg plus a calcium-channel blockerNCT00134160Risk of bias negative
candesartan
Takahashi, 2006candesartancontrolExploratory negative
E-COST, 2005candesartanconventional treatmentRisk of bias suggesting
E-COST-R, 2005candesartanconventional treatmentRisk of bias negative
HIJ-CREATE, 2009candesartanconventional treatmentRisk of bias suggesting
SCOPE, 2003candesartanplaceboLow risk of bias negative
TROPHY, 2006candesartanplaceboNCT00227318Exploratory suggesting
CASE-J, 2008candesartanamlodipineRisk of bias suggesting
ALPINE, 2003candesartanhydrochlorothiazideLow risk of bias suggesting
irbesartan
IDNT (irbesartan vs pbo), 2001irbesartanplaceboLow risk of bias negative
IRMA 2, 2001irbesartanplaceboLow risk of bias negative
losartan
RENAAL, 2001losartanplaceboLow risk of bias -
LIFE, 2002losartanatenololLow risk of bias suggesting
olmesartan
ROADMAP, 2010olmesartanplaceboNCT00185159Low risk of bias suggesting
ORIENTolmesartanplaceboNCT00141453negative
ramipril
ONTARGET (association vs ramipril), 2008telmisartan + ramiprilramiprilNCT00153101negative
ONTARGET (association vs telmisartan), 2008telmisartan + ramipriltelmisartanNCT00153101suggesting
telmisartan
TRANSCEND, 2008telmisartanplaceboNCT00153101Low risk of bias suggesting
PROPHESS, 2008telmisartanplaceboNCT00153062Low risk of bias negative
ONTARGET (telmisartan alone), 2008telmisartanramiprilNCT00153101Low risk of bias suggesting