miscellaneous

     

Select            
Trial Studied trt Control trt patientstagsROB Trial result

angiotensin-receptor blockers

not classified
Suzuki, 2008     ARBscontrolRisk of bias negative
Ruilope, 2010   LCZ696placeboLow risk of bias -
IDNT (irbesartan vs amlodipine), 2001     irbesartanamlodipineLow risk of bias negative
VALUE, 2004      NCTvalsartanamlodipineLow risk of bias suggesting
DETAIL, 2004     telmisartanenalaprilLow risk of bias negative
OSCAR, 2011      NCTolmesartan 40 mgolmesartan 20 mg plus a calcium-channel blockerRisk of bias negative
candesartan
Takahashi, 2006     candesartancontrolExploratory negative
E-COST, 2005     candesartanconventional treatmentRisk of bias suggesting
E-COST-R, 2005     candesartanconventional treatmentRisk of bias negative
HIJ-CREATE, 2009     candesartanconventional treatmentRisk of bias suggesting
SCOPE, 2003   candesartanplaceboLow risk of bias negative
TROPHY, 2006      NCTcandesartanplaceboLow risk of bias suggesting
CASE-J, 2008     candesartanamlodipineRisk of bias suggesting
ALPINE, 2003   candesartanhydrochlorothiazideLow risk of bias suggesting
irbesartan
IDNT (irbesartan vs pbo), 2001       irbesartanplaceboLow risk of bias negative
IRMA 2, 2001     irbesartanplaceboLow risk of bias negative
losartan
RENAAL, 2001     losartanplaceboLow risk of bias -
LIFE, 2002     losartanatenololLow risk of bias suggesting
olmesartan
ROADMAP, 2010        NCTolmesartanplaceboLow risk of bias suggesting
ORIENT    NCTolmesartanplaceboLow risk of bias negative
ramipril
ONTARGET (association vs ramipril), 2008    NCTtelmisartan + ramiprilramiprilLow risk of bias negative
ONTARGET (association vs telmisartan), 2008    NCTtelmisartan + ramipriltelmisartanLow risk of bias suggesting
telmisartan
TRANSCEND, 2008    NCTtelmisartanplaceboLow risk of bias suggesting
PROPHESS, 2008      NCTtelmisartanplaceboLow risk of bias negative
ONTARGET (telmisartan alone), 2008      NCTtelmisartanramiprilLow risk of bias suggesting