aromatase inhibitors

Aminoglutethimide - Anastrozole - Exemestane - Fadrozole - Formestane - Letrozole      

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Trial Studied trt Control trt patientstagsROB Trial result

advanced breast cancer (metastatic)

aminoglutethimide
Mercer, 1993   aminoglutethimidehydrocortisone -
Canney, 1988   aminoglutethimidemedroxyprogesterone acetate -
Garcia-Giralt, 1992   aminoglutethimidemedroxyprogesterone acetate -
Samonis, 1994   aminoglutethimidemedroxyprogesterone acetate -
Lundgren, 1989   aminoglutethimidemegestrol acetate -
Russell, 1997   aminoglutethimidemegestrol acetate -
Alonso-Munoz, 1988   aminoglutethimidetamoxifen -
Gale, 1994   aminoglutethimidetamoxifen -
Ingle, 1986   aminoglutethimide + tamoxifentamoxifen -
Powles, 1984   combination of hormone therapiestamoxifen -
anastrozole
Mauriac, 2003   anastrozolefulvestrant -
Buzdar a, 1996   anastrozolemegestrol acetate -
TARGET (Bonneterre), 2001   anastrozoletamoxifen -
Milla-Santos, 2003   anastrozoletamoxifen -
exemestane
Chia, 2008   exemestanefulvestrant -
Kaufmann, 2000   exemestanemegestrol acetate -
Paridaens, 2003   exemestanetamoxifen -
fadrozole
Bezwoda, 1998   fadrozolemegestrol acetate -
Buzdar b, 1996   fadrozolemegestrol acetate -
Buzdar c, 1996   fadrozolemegestrol acetate -
Thuerlimann, 1996   fadrozoletamoxifen -
Falkson, 1996   fadrozoletamoxifen -
formestane
Kleeberg, 1997   formestaneanastrozole -
Thuerlimann, 1997   formestanemegestrol acetate -
Freue, 2000   formestanemegestrol acetate -
Perez Carrion, 1994   formestanetamoxifen -
letrozole
Gershanovich, 1998   letrozoleaminoglutethimide -
Rose, 2003   letrozoleanastrozole -
Goss, 2007   letrozoleatamestane + toremifene -
Tominaga, 2003   letrozolefadrozole -
Buzdar, 2001   letrozolemegestrol acetate -
Dombernowsky, 1998   letrozolemegestrol acetate -
Mourisden, 2001   letrozoletamoxifen -