aromatase inhibitors

Aminoglutethimide - Anastrozole - Exemestane - Fadrozole - Formestane - Letrozole      

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Trial Studied trt Control trt patientstagsROB Trial result

advanced breast cancer (metastatic)

aminoglutethimide
Mercer, 1993   aminoglutethimidehydrocortisonenegative
Canney, 1988   aminoglutethimidemedroxyprogesterone acetatesuggesting
Garcia-Giralt, 1992   aminoglutethimidemedroxyprogesterone acetatenegative
Samonis, 1994   aminoglutethimidemedroxyprogesterone acetatenegative
Lundgren, 1989   aminoglutethimidemegestrol acetatenegative
Russell, 1997   aminoglutethimidemegestrol acetatenegative
Alonso-Munoz, 1988   aminoglutethimidetamoxifennegative
Gale, 1994   aminoglutethimidetamoxifennegative
Ingle, 1986   aminoglutethimide + tamoxifentamoxifennegative
Powles, 1984   combination of hormone therapiestamoxifennegative
anastrozole
Mauriac, 2003   anastrozolefulvestrantnegative
Buzdar a, 1996   anastrozolemegestrol acetatenegative
TARGET (Bonneterre), 2001   anastrozoletamoxifensuggesting
Milla-Santos, 2003   anastrozoletamoxifennegative
exemestane
Chia, 2008   exemestanefulvestrantnegative
Kaufmann, 2000   exemestanemegestrol acetatenegative
Paridaens, 2003   exemestanetamoxifennegative
fadrozole
Bezwoda, 1998   fadrozolemegestrol acetatenegative
Buzdar b, 1996   fadrozolemegestrol acetatenegative
Buzdar c, 1996   fadrozolemegestrol acetatenegative
Thuerlimann, 1996   fadrozoletamoxifennegative
Falkson, 1996   fadrozoletamoxifennegative
formestane
Kleeberg, 1997   formestaneanastrozolenegative
Thuerlimann, 1997   formestanemegestrol acetatenegative
Freue, 2000   formestanemegestrol acetatesuggesting
Perez Carrion, 1994   formestanetamoxifennegative
letrozole
Gershanovich, 1998   letrozoleaminoglutethimidenegative
Rose, 2003   letrozoleanastrozolenegative
Goss, 2007   letrozoleatamestane + toremifenenegative
Tominaga, 2003   letrozolefadrozolenegative
Buzdar, 2001   letrozolemegestrol acetatesuggesting
Dombernowsky, 1998   letrozolemegestrol acetatenegative
Mourisden, 2001   letrozoletamoxifennegative