selective estrogen receptor modulator (SERM)

Tamoxifen - Toremifene      

Select            
Trial Studied trt Control trt patientstagsROB Trial result

advanced breast cancer (metastatic)

tamoxifen
Viladiu, 1985      -
Kuss, 1997     tamoxifen -
De Lena, 1990     tamoxifen -
Takatsuka, 1989     tamoxifen 20 mg/day40 mg/day -
Ingle, 1986     tamoxifenbilateral oophorectomy -
Perry, 1985     tamoxifen + CATCAT -
Mouridsen, 1985     tamoxifen + CMFCMF -
Spooner, 1991     loading dose regimen of tamoxifenconventional dosing -
Gockerman, 1986     tamoxifendiethylstilbestrol -
Beex, 2006         intermittent tamoxifenIntermittent tamoxifen -
Muss, 1994       tamoxifenmedroxyprogesterone -
Castiglione-Gertsch, 1993     tamoxifenmedroxyprogesterone acetate -
van, 1986     tamoxifenmedroxyprogesterone acetate -
Stuart, 1996     tamoxifenmegestrol acetate -
Gill, 1993     tamoxifenmegestrol acetate -
Ettinger, 1986     tamoxifenmegestrol acetate -
Kellokumpu-Lehtinen, 1987     tamoxifennandrolone decanoate -
Beelen, 2014     tamoxifenno systemic treatment -
Sawka, 1997     tamoxifenovarian ablation -
Willsher, 1996     tamoxifenradiotherapy -
Mauriac, 1986     alternatingsuccessive -
Buchanan, 1986     tamoxifensurgical oophorectomy -
toremifene
Nomura, 1993   toremifenetamoxifenLow risk of bias negative
Gershanovich, 1997   toremifenetamoxifennegative
Milla-Santos, 2001   toremifenetamoxifenLow risk of bias negative
Hayes, 1995   toremifenetamoxifennegative
Stenbygaard, 1993   toremifenetamoxifennegative
Pyrhonen, 1997   toremifenetamoxifensuggesting