nontaxane microtubule dynamics inhibitor

Eribulin      

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Trial Studied trt Control trt patientstagsNCTROB Result

advanced breast cancer (metastatic)

eribulin
Trial 301 (Kaufman), 2015eribulincapecitabineNCT00337103Risk of bias negative
SCRI BRE 197 ongoing eribulin+cyclophosphamidedocetaxel+cyclophosphamideNCT01527487 ongoing
Vahdat, 2013eribulinixabepiloneNCT00879086Exploratory -
NCT02037529 ongoing eribulinpaclitaxelNCT02037529Risk of bias ongoing
2014-0857 ongoing eribulin+gemcitabinepaclitaxel+gemcitabineNCT02263495Exploratory ongoing
EMBRACE (Cortes), 2011eribulintreatment of physicianNCT00388726Risk of bias conclusive
E7389-C086-304 ongoing eribulinvinorelbineNCT02225470Exploratory ongoing