ovarian cancer  

     

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Trial Studied trt Control trt patientstagsNCTROB Result

poly ADP-ribose polymerase (PARP) inhibitor

niraparib
ENGOT-OV16/NOVA non-gBRCAniraparibplaceboNCT01847274Low risk of bias suggesting
ENGOT-OV16/NOVA gBRCA, 2017niraparibplacebo BRCA-mutated NCT01847274Low risk of bias suggesting
olaparib
SOLO2/ENGOT-Ov21olaparibplacebo BRCA-mutated NCT01874353Low risk of bias suggesting
Ledermann, 2012olaparidplaceboNCT00753545Exploratory suggesting
rucaparib
ARIEL 4 ongoing rucaparibchemotherapyRelapsed BRCA Mutant BRCA-mutated NCT02855944Risk of bias ongoing
ARIEL 3 ongoing rucaparibplaceboNCT01968213Low risk of bias ongoing