familial hypercholesterolemia clinical trials results

ezetimibe versus placebo
Enhance, 2008
ezetimibe 10mg + simvastatin daily
versus
simvastatin 80mg daily
patients with familial hypercholesterolemiadouble blind
Follow-up duration: 24 months
pactimibe versus placebo
CAPTIVATE, 2009
NCT00151788
pactimibe 100mg daily
versus
placebo
patients with familial hypercholesterolemia and carotid atherosclerosis double blind
Follow-up duration: 15 months (mean)
United States, Canada, Europe, South Africa, Israel
torcetrapib versus placebo (on top of atorvastatin)
RADIANCE 1, 2007
NCT00136981
atorvastatin combined with 60 mg of torcetrapib
versus
atorvastatin monotherapy
patients with heterozygous familial hypercholesterolemia open
Follow-up duration: 24 months