diabetic kidney disease clinical trials results

amlodipine versus placebo
IDNT amlodipine, 2001
Amlodipine 10 mg daily
versus
placebo
hypertensive patients with nephropathy due to type 2 diabetesdouble-blind
Follow-up duration: 2.6 years
Worldwide
fosinopril versus control
Fogari, 2002
amlodipine plus fosinopril (5/10 to 15/30 mg/day
versus
amlodipine (5 to 15 mg/day)
hypertensive patients with type 2 diabetes and microalbuminuria NA
Follow-up duration: NA
irbesartan versus amlodipine
IDNT (irbesartan vs amlodipine), 2001
Irbesartan 300 mg daily
versus
amlodipine 10 mg daily
hypertensive patients with nephropathy due to type 2 diabetes double blind
Follow-up duration: 2.6 years
Worldwide
irbesartan versus placebo
IDNT irbesartan, 2001
Irbesartan 300 mg daily
versus
placebo
hypertensive patients with nephropathy due to type 2 diabetes double blind
Follow-up duration: 2.6 years
Worldwide
IPDM 150mg, 2001
irbesartan 150 mg daily
versus
placebo
hypertensive patients with type 2 diabetes and microalbuminuriadouble-blind
Follow-up duration: 2 years
Worldwide
losartan versus placebo
RENAAL, 2001
losartan 50 to 100 mg once daily
versus
placebo
patients with type 2 diabetes and nephropathydouble-blind
Follow-up duration: 3.4 y
America, Europe, Asia
olmesartan versus placebo
ORIENT,
NCT00141453
olmesartan
versus
placebo
patients with diabetic Nephropathy and overt proteinuria secondary to type 2 diabetes mellitusdouble-blind
Japan, Hong Kong
ramipril versus placebo
DIABHYCAR, 2004
ramipril 1.25 mg/day
versus
placebo
patients with type 2 diabetes who have microalbuminuria or proteinuriadouble-blind
Follow-up duration: median 4 years
Europe, North Africa
telmisartan versus enalapril
DETAIL, 2004
telmisartan 80 mg daily
versus
enalapril 20 mg daily
subjects with type 2 diabetes and early nephropathy double-blind
Follow-up duration: 5 year
temisartan versus enalapril
DETAIL, 2004
telmisartan 80 mg daily
versus
enalapril 20 mg daily
subjects with type 2 diabetes and early nephropathydouble-blind
Follow-up duration: 5 years
northern Europe