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antiplatelets drug in acute coronary syndrome for patients with scheduled percutaneous coronary intervention , clinical trials results

ASA high dose versus ASA low dose
CURRENT - OASIS 7 (ASA), 2010
NCT00335452
High-dose aspirin
versus
Low-dose aspirin
ACS patients referred for an invasive strategy (scheduled for percutaneous coronary intervention no more than 72 hours after randomization) open
Follow-up duration: 30 days
clopidogrel high-dose regimen versus clopidogrel standard-dose
CURRENT OASIS 7 (clopidogrel), 2010
NCT00335452
Double-dose clopidogrel
versus
Standard-dose clopidogrel
ACS patients referred for an invasive strategy (scheduled for percutaneous coronary intervention no more than 72 hours after randomization)open
Follow-up duration: 30 days
prasugrel versus clopidogrel
TRITON-TIMI 38, 2007
NCT00097591
prasugrel 60-mg loading dose and 10-mg daily maintenance dose, for 6 to 15 months
versus
clopidogrel (a 300-mg loading dose and a 75-mg daily maintenance dose) for 6 to 15 months
patients with moderate-to-high-risk acute coronary syndromes (UA, NSTEMI,STEMI) with scheduled percutaneous coronary interventiondouble blind
30 countries

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