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Drug eluting stent in coronary artery disease for bifurcation lesion, clinical trials results

double stenting with PES versus single stenting
BBC ONE, 2008
NCT00351260
systematically stenting of both vessels with drug eluting stents(culotte or crush techniques) and with mandatory kissing balloon dilatation
versus
stenting of the main vessel followed by optional kissing balloon dilatation/T-stent
patients with significant coronary bifurcation lesions open
Follow-up duration: 9 months
double stenting with SES versus single stenting
CACTUS , 2009
elective
versus
stenting of only the main branch, with provisional side-branch T-stenting
patients with true coronary bifurcation lesionsopen
Follow-up duration: 6 months
Europe
Colombo, 2004
stenting of both branches using sirolimus-eluting stent
versus
stenting of the main branch with provisional stenting of the side branch
patients with coronary bifurcation lesionsopen
Follow-up duration: 6.4 months
Italy
Ferenc, 2008
routine T-stenting with sirolimus-eluting stents in both branches
versus
provisional T-stenting with SES placement in the main branch followed by kissing-balloon angioplasty and provisional SES placement in the side branch only for inadequate results
patients with a coronary bifurcation lesionopen
Follow-up duration: 12 months
NORDIC , 2006
stenting with sirolimus-eluting stents of both main vessel and side branch
versus
stenting with sirolimus-eluting stent of main vessel and optional stenting of side branch
patients with a coronary bifurcation lesion open
Follow-up duration: 14 months
Pan, 2004
Double stenting of both main and side branche
versus
single stenting of the main vessel only
patients with true coronary bifurcation lesionsopen
Follow-up duration: 11 months
kissing balloon versus no kissing balloon
Nordic-Baltic Bifurcation Study III, 2009
NCT00914199
Kissing balloon dilatation post-stenting of the main artery (one-stent technique)
versus
no kissing balloon dilatation
patients with bifurcation lesionsopen
Follow-up duration: 6 mo
Denmark, Finland, Latvia, Sweden, Norway
sirolimus eluting stent versus paclitaxel eluting stent
Pan, 2007
SES for provisional T-stenting
versus
PES for provisional T-stenting
patients with bifurcation lesionsopen
Follow-up duration: 24 months (mean)
Spain

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