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myocardial revascularization in stable angina for single vessel disease, clinical trials results

angioplasty versus MIDCAB
AMIST (Reeves), 2004
percutaneous transluminal coronary angioplasty (PTCA) with or without stenting
versus
minimally invasive direct coronary artery bypass grafting (MIDCAB)
single-vessel disease (at least 50% stenosis) of the left anterior descending coronary artery (LAD). open
Follow-up duration: 12 months
England
balloon angioplasty versus CABG
MASS, 1995
percutaneous transluminal coronaryangioplasty
versus
mammary bypass surgery
patients with stable angina,normal ventricular function and a proximal stenosis of the leftanterior descending coronary artery >80%open
Follow-up duration: 3.2 y
Brazil
Lausanne, 1994
transluminal coronary angioplasty
versus
Coronary artery bypass grafting
patients with isolated proximal left anterior descending artery stenosis, conserved left ventricular function, and documented ischaemiaopen
Follow-up duration: 3.2 y
Switzerland
balloon angioplasty versus medical treatment
ACME, 1992
PTCA within 3 days of randomization
versus
medical treatment (nitrates, beta-blockers, calcium blockers)
Stable angina, history of angina, MIwithin 3 months, exercise test with STdepression >3 mm, no previous PTCA; Single or serial stenosis within sameartery 70% to 99% proximal twothirdsopen
Follow-up duration: 5y
US
MASS, 1995
PTCA
versus
medical treatment (aspirin, nitrates, beta-blockers and calcium channel blocking
Stable angina, no Q wave MI, no leftventricular dysfunction^¾„open
Follow-up duration: 5y
Brazil
Sievers, 1993
PTCA
versus
medical treatment
Previous non­Q wave MI, no angina indaily life, no previous Q wave MIopen
Follow-up duration: 2y
Germany
PCI with or without stent versus medical treatment
ALKK, 2003
angioplasty
versus
medical therapy
patients with single vessel disease of the infarct vessel and no or minor angina pectoris in the subacute phase (1 to 6 weeks) after an acute myocardial infarction open
Follow-up duration: 4.7y
Germany
PCI withdrug-eluting stents versus CABG
Hong, 2005
drug-eluting stents
versus
invasive direct coronary artery bypass (MIDCAB) surgery
proximal left anterior descending (LAD) coronary artery stenosisopen
Follow-up duration: 9 months
PCI withsirolimus ES versus MIDCAB
Thiele, 2009
NCT00299429
sirolimus-eluting stent
versus
MIDCAB surgery
isolated LAD diseaseopen
Follow-up duration: 12 months
Germany
stent versus CABG
LEMANS, 2002
NCT00375063
unprotected left main stenting
versus
coronary artery bypass grafting
patients with unprotected left main coronary artery stenosisopen
Follow-up duration: 1y
Poland
stent versus E-ACAB
Cisowski, 0
Tristar, Tera, Penta (Guidant) (Cordis)
versus
endoscopic atraumatic coronary artery bypass grafting
single vessel disease ACC/AHA A or B lesion in proximal LAD Angina CCS II or higher Lesion diameter 3 mm orgreater/length 20mm or greateropen
Follow-up duration: 2 years
Poland
stent versus MIDCAB
Diegeler, 2002
Various stents
versus
minimally invasive direct coronary artery bypass (off-pump proceedure)
single vessel disease Lesion =75% stenosis in proximal LAD or between origin of left circumflex and 1st septal branchopen
Follow-up duration: 5 years
Germany
Drenth, 2002
Stent type not reported
versus
minimally invasive direct coronary artery bypass (off-pump proceedure
single vessel disease Angina II Lesion (Grade B2 or C) of proximal LAD Suitable for CABG or stentingopen
Follow-up duration: 6 months, 3 years
Netherlands
Grip, 2001
Stent type not reported
versus
minimally invasive direct coronary artery bypass (off-pump proceedure)
single vessel disease engaging LAD Stable or unstable anginaopen
Sweden
SIMA, 2000
Any CE marked, but Palmaz-Schatz recommended
versus
Conventional CABG or minimally invasive direct coronary artery bypass (off-pump proceedure) (10% of surgical procedures
single vessel disease Symptomatic or silent ischaemia 1 LAD lesion Ejection fraction >45% Vessel >3.0mmopen
Follow-up duration: 2.4 years
Europe

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