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myocardial revascularization in stable angina for diabetic patients , clinical trials results

CABG or PCI versus medical treatment
BARI 2D, 2009
NCT00006305
prompt revascularization with intensive medical therapy
versus
intensive medical therapy alone
patients with type 2 diabetes and heart diseaseopen
Follow-up duration: 5.3 y
US, Canada, Brazil, Mexico, Czech Republic, Austria
PCI with drug-eluting stents versus CABG
SYNTAX (diabetic), 2010
NCT00114972
paclitaxel-eluting stents
versus
surgical revascularization
sub group of diabetic patients with left main and/or 3-vessel disease
Follow-up duration: 1 year
FREEDOM, 2012
NCT00086450
percutaneous coronary stenting
versus
CABG
patients with diabetes and multivessel coronary artery diseaseopen
Follow-up duration: 3.8 yrs (median)
international
sirolimus eluting stent versus bare-metal stent
DESSERT, 2008
Cypher andCypher Select
versus
Sonic (Cordis)
de novo lesions of diabetic patients treated with insulin and/or oral antidiabetics for >3 monthssingle-blind
Follow-up duration: 12 months
Italy
sirolimus eluting stent versus paclitaxel eluting stent
Kim, 2008
Cypher
versus
Taxus
Korean diabetic patients with high-grade de novo coronary lesions (stenosis of>70 percent of the luminal diameter) requiring <3 stentsopen
Follow-up duration: 6 months
Korea
stent versus CABG
CARDia (PCI), 2008
ISRCTN19872154
PCI plus stenting (and routine abciximab)
versus
CABG
Patients with diabetes and symptomatic multivessel coronary artery disease or complex single-vessel disease. open
Follow-up duration: 1 y
UK, Ireland

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