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cholesterol lowering intervention in aortic stenosis for all type of patients, clinical trials results

atorvastatin versus placebo
SALTIRE, 2005
atorvastatin 80mg daily
versus
placebo
patients with calcific aortic stenosisdouble blind
Follow-up duration: 25 mo (7-36)
ezetimibe+simvastatin versus placebo
SEAS, 2008
NCT00092677
simvastatin 40mg plus ezetimibe 10 mg daily
versus
placebo
patients with mild-tomoderate, asymptomatic aortic stenosisdouble blind
Follow-up duration: 52.2 mo
Europe
rosuvastatin versus placebo
ASTRONOMER, 2010
ISRCTN 32424163
rosuvastatin 40 mg daily
versus
placebo
asymptomatic patients with mild to moderate aortic stenosis and no clinical indications for cholesterol loweringdouble blind
Follow-up duration: 3.5 y

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