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prevention in post stroke for patients with prior stroke or TIA, clinical trials results

folic acid, vit B12 and vit B6 versus placebo
VITATOPS, 2010
NCT00097669ÐX&
folic acid and vitamins B12 and B6 in a single tablet
versus
placebo
patients with recent stroke or TIA (within the past seven months)double-blind
Follow-up duration: 3.4 y
20 countries
high dose - folic acid, vit B12 and vit B6 versus low dose - folic acid, vit B12 and vit B6
VISP (Toole), 2004
high-dose of folic acid, pyridoxine (vitamin B6), and cobalamin (vitamin B12)
versus
low-dose of folic acid, pyridoxine (vitamin B6), and cobalamin (vitamin B12)
adults with nondisabling cerebral infarctiondouble blind
Follow-up duration: 2 y
United States, Canada, Scotland

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