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dietary salt reduction in cardiovascular prevention for all type of patients, clinical trials results

sodium reduction versus control
HPT, 1990
dietary counseling
versus
no dietary counseling
normotensive healthy men and women aged 25 to 49 years, with diastolic blood pressures of 78 to 89 mm Hgopen
Follow-up duration: 3 years
USA
TOHP I, 1992
sodium reduction
versus
unmasked nonintervention controls
men and women, aged 30 through 54 years, with diastolic blood pressure from 80 through 89 mm Hg open
Follow-up duration: 18 months
USA
TOHP II, 1997
sodium reduction intervention
versus
control
overweight people with high-normal blood pressureopen
Follow-up duration: 3-4 years
USA
Chang, 2006
potassium-enriched salt
versus
control
elderly veteransopen
Follow-up duration: 31 mo
USA
Morgan, 1978
moderate restriction of salt
versus
control
patients with a diastolic blood-pressure between 95 and 109 mm Hg open
Follow-up duration: 2 years
Australia
TONE, 1998
reduced sodium intake
versus
control
older persons with hypertensionopen
Follow-up duration: 29 months
USA
Alli, 1992
low-sodium diet
versus
usual diet
previously undiagnosed mildly hypertensive patients open
Follow-up duration: 12 months
Italy
Arroll, 1995
salt restriction
versus
without salt restriction
healthy adult volunteers with a sedentary lifestyle and on pharmacological therapy for hypertension open
Follow-up duration: 6 months
New Zealand
Costa, 1981
low-salt diet
versus
control
young patients with borderline hypertension open
Follow-up duration: 12 months
Italy
DISH, 1985
sodium-restriction
versus
control
normotensive subjectopen
Follow-up duration: 56 weeks
Kumanyika, 1993
reduce dietary sodium to 80 mmol (1800 mg)/24 h
versus
Morgan, 1987
reduced sodium intake
versus
control
hypertensive patients previously well-controlled on drug therapyopen
Follow-up duration: 6 months
Australia
Paterna, 2008
low-sodium diet plus oral furosemide (250-500 mg, b.i.d.)
versus
normal-sodium diet plus oral furosemide 250-500 mg, b.i.d. (twice a day) and fluid intake of 1000 ml per day
compensated CHF patients open
Follow-up duration: 180 days
Silman, 1993
restricted sodium diet
versus
control
patients who had a sustained diastolic blood pressure of 95 to 104 mm Hg and who had no treatment for it for at least 13 months before the trialopen
Follow-up duration: 13 months
UK
Thaler, 1982
salt-restriction
versus
control
subjects aged 64 or less with a systolic blood pressure 138-179 mmHg including those on antihypertensive treatmentopen
New Zealand

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