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mineralocorticoid receptor antagonists in heart failure for HF pEF, clinical trials results

spironolactone versus placebo
TOPCAT, 2014
NCT00094302
spironolactone (15 to 45 mg daily)
versus
placebo
patients with heart failure and a preserved left ventricular ejection fraction of 45% or more double-blind
Follow-up duration: 3.3 years

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