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Exercise Therapy in heart failure for all type of patients, clinical trials results

Exercise training versus control
Dubach et al, 1997
Supervised walking, two hours daily; supervised cycling 40minutes four days a week
versus
control
patients with chronic heart failure open
Follow-up duration: 0.7 y
Switzerland
Giannuzzi et al, 1997
Supervised cycling, 30 minutesthree days a week for two months, then home based 30 minutes for three days a week and walking for 30 minutes
versus
control
patients with <40% ejection fraction after a first Q-wave myocardial infarction open
Follow-up duration: 0.6 y
Italy
Belardinelli et al, 1999
Supervised cycling, 60 minutes three days a week for eightweeks, then two days a week
versus
no exercise
patients with CHF open
Follow-up duration: 3.1 y
Italy
Hambrecht et al, 1995
Supervised and home based walking, calisthenics, cycling40-60 minutes a day
versus
physically inactive control group
patients with chronic heart failure open
Follow-up duration: 0.4 y
Germany
ExTraMATCH, 2004

versus
Kiilavuori et al, 2000
Supervised cycling 30 minutes three days a week for three months, then home basedtraining (walking, cycling,rowing, and swimming)
versus
control
patients with stable NYHA class II-III CHFopen
Follow-up duration: 6.3 y
Finland
McKelvie et al, 2002
Supervised aerobic (cycling,treadmill, arm) and resistance training 30 minutes three days a week for three months, then home based aerobic training three days a week
versus
usual care
patients in NYHA class I to III, with ejection fraction <40% and 6-minute walk distance <500 meterssingle blind
Follow-up duration: 1.5 y
Canada
Zanelli et al, 1997
Supervised aerobic (cycling,treadmill, arm) and resistance training 30 minutes two days a week and home based cycling three days a week for two months, then only home based aerobic training five days a week
versus

Follow-up duration: 0.8 y
Italy
Wielenga et al, 1999
Supervised cycling, walking,ball game 30 minutes threedays a week for eight weeks, then two days a week
versus
control
patients with chronic heart failure NYHA II-III open
Follow-up duration: 3.9 y
Netherlands
Willenheimer et al, 1998
Supervised interval cyclingtraining (90 second exercise and 30 second rest) for 15-45 minutes two days a weekc
versus
control
patients with stable mild-to-moderate heart failure open
Follow-up duration: 4.4 y
Sweden
structured exercise training versus control
HF-ACTION, 2008
NCT00047437
highly structured exercise program focused on increasing workout intensity and duration
versus
usual care,including recommendations for daily exercise
heart-failure patients (NYHA class 2-4, ejection fraction <35%) open
Follow-up duration: mean 2.5 y
USA, Canada, France

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