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cholesterol lowering intervention in CABG surgery for preoperative statins, clinical trials results

preoperative atorvastatin versus placebo
Chello et al., 2006
preoperative atorvastatin 20 mg/d, started 3 wks before surgery
versus
placebo
elective CABGdouble blind
Follow-up duration: 7 days
Patti et al., 2006
preoperative atorvastatin 40 mg/d, starting 7 days before operation
versus
placebo
patients undergoing elective cardiac surgery with cardiopulmonary bypass, without previous statin treatment or history of AFdouble blind
Follow-up duration: 30 days
preoperative simvastatin versus no treatment
Christenson, 1999
preoperative simvastatin 20 mg/d, stated 4 weeks before surgery
versus
no statins
patients with hypercholesterolemia (total cholesterol > or =6.2 mmol/l) planned for CABG
Follow-up duration: 7 days

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