Patel, 2005 trial summary

A randomised clinical trial investigating the effect of Bone marrow progenitor cells versus control in patients with ischemic cardiomyopathy and an ejection fraction of less than 35% who were scheduled for primary off-pump coronary artery bypass grafting

J Thorac Cardiovasc Surg 2005;130:1631-8  




Studied treatment adult autologous stem cell transplantation (CD34+)
Control treatment



Patients patients with ischemic cardiomyopathy and an ejection fraction of less than 35% who were scheduled for primary off-pump coronary artery bypass grafting
Group sizes 10 / 10



Blindness Inclusion period
Follow-up duration Centers
Lost to FU geographical localisation
Primary endpoint Design



EndpointX1N1X0N0TE95% CI Minnesota Living With Heart Failure Questionnaire - -9 - -9 no data 6-min Walk, m - -9 - -9 no data all-cause mortality - -9 - -9 no data LVEF - -9 - -9 no data acute heart failure - -9 - -9 no data LV End-Systolic Volume - -9 - -9 no data ventricular tachycardia - -9 - -9 no data NT-proBNP - -9 - -9 no data NYHA deterioration - -9 - -9 no data Peak VO2 (mL/kg/min) - -9 - -9 no data NYHA class - -9 - -9 no data cardiac event - 10 - 10 no data0,22,01,0


Patel AN, Geffner L, Vina RF, Saslavsky J, Urschel HC Jr, Kormos R, Benetti F Surgical treatment for congestive heart failure with autologous adult stem cell transplantation: a prospective randomized study. J Thorac Cardiovasc Surg 2005;130:1631-8     [PMID: 16308009]   link to pdf  



Registering number (see trial on clinicaltrials.gov)
Code Name

 




Appears in following systematic reviews: