Manginas, 2007 trial summary

A randomised clinical trial investigating the effect of Bone marrow progenitor cells versus control in patients with old, nonviable anterior myocardial infarction

Catheter Cardiovasc Interv 2007;69:773-81  




Studied treatment intracoronary administration of selected CD133(+) and CD133(-)CD34(+) progenitor cells
Control treatment



Patients patients with old, nonviable anterior myocardial infarction
Group sizes -9 / -9



Blindness Inclusion period
Follow-up duration Centers
Lost to FU geographical localisation
Primary endpoint Design



EndpointX1N1X0N0TE95% CI ventricular tachycardia - -9 - -9 no data NT-proBNP - -9 - -9 no data NYHA deterioration - -9 - -9 no data Peak VO2 (mL/kg/min) - -9 - -9 no data NYHA class - -9 - -9 no data cardiac event - -9 - -9 no data Minnesota Living With Heart Failure Questionnaire - -9 - -9 no data 6-min Walk, m - -9 - -9 no data all-cause mortality - -9 - -9 no data LVEF - -9 - -9 no data acute heart failure - -9 - -9 no data LV End-Systolic Volume - -9 - -9 no data0,22,01,0


Manginas A, Goussetis E, Koutelou M, Karatasakis G, Peristeri I, Theodorakos A, Leontiadis E, Plessas N, Theodosaki M, Graphakos S, Cokkinos DV Pilot study to evaluate the safety and feasibility of intracoronary CD133(+) and CD133(-) CD34(+) cell therapy in patients with nonviable anterior myocardial infarction. Catheter Cardiovasc Interv 2007;69:773-81     [PMID: 17394248]   link to pdf  



Registering number (see trial on clinicaltrials.gov)
Code Name

 




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