NESTOR, 2004 trial summary

A randomised clinical trial investigating the effect of versus in

J Hypertens 2004;22:1613-22  




Studied treatment
Control treatment



Patients
Group sizes -9 / -9
Duration of diabetes
Duration of hypertension
Glycosylated hemoglobin
BP (systolic/diastolic)
subgroup
hypertension (%)
nephropathy
primary population
BMI
BMI (kg/m²)
history of cardiovascular disease



Blindness Inclusion period
Follow-up duration Centers
Lost to FU geographical localisation
Primary endpoint Design
study population
fasting glucose (mmol/l)



EndpointX1N1X0N0TE95% CI Cardiovascular events - -9 - -9 no data Cardiovascular death - -9 - -9 no data Fatal and nonfatal MI - -9 - -9 no data Stroke - -9 - -9 no data All deaths - -9 - -9 no data macro + micro-vascular events - -9 - -9 no data microvascular events - -9 - -9 no data non fatal stroke - -9 - -9 no data non fatal MI - -9 - -9 no data DBP at end (mmHg) - -9 - -9 no data SBP (mmHg) - -9 - -9 no data DBP (mmHg) - -9 - -9 no data new or worsening nephropathy - -9 - -9 no data new microalbuminuria - -9 - -9 no data peripheral arterial disease - -9 - -9 no data heart failuer (fatal and non fatal) - -9 - -9 no data Doubling of serum creatinine - -9 - -9 no data SBP at end (mmHg) - -9 - -9 no data DBP change (mmHg) - -9 - -9 no data SBP change (mmHg) - -9 - -9 no data new or worsening retinopathy - -9 - -9 no data visual deterioration - -9 - -9 no data renal death - -9 - -9 no data Death related to diabetes - -9 - -9 no data0,22,01,0


Marre M, Puig JG, Kokot F, Fernandez M, Jermendy G, Opie L, Moyseev V, Scheen A, Ionescu-Tirgoviste C, Saldanha MH, Halabe A, Williams B, Mion Júnior D, Ruiz M, Hermansen K, Tuomilehto J, Finizola B, Gallois Y, Amouyel P, Ollivier JP, Asmar R Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study. J Hypertens 2004;22:1613-22     [PMID: 15257186]   link to pdf  



Registering number (see trial on clinicaltrials.gov)
Code Name

 




Appears in following systematic reviews: