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antithrombotics in thrombosis prevention for arthroscopy, clinical trials results

deltaparin versus control
Michot, 2002
deltaparin 2500IU 60-120min before procedure, followed 6hrs after the end of the procedure by 2500IU (<70kg) or 5000 IU(>70kg)
versus
no treatment
patients requiring diagnostic or therapeutic arthoscopic knee surgery as outpatients; aged18 to 80 years.open
Follow-up duration: 30 days
Switzerland.
enoxaparin versus control
Canata, 2003
enoxaparin sc daily (dose not specified)
versus
no treatment
ACL reconstruction for symptomatic ACL-deficient knees
Follow-up duration: 6 days
Italy
extended-duration thromboprophylaxis versus standard-duration thromboprophylaxis
Marlovits, 2007
extended-duration thromboprophylaxis with enoxaparin for 20 days
versus
standard thromboprophylaxis with enoxaparin (3 to 8 days)
patients who had undergone arthroscopic surgery of the anterior cruciate ligamentdouble-blind
Follow-up duration: <=28 days
Austria
nadroparin versus control
KANT (7 days), 2008
once-daily subcutaneous injection of LMWH (nadroparin, 3800 anti-Xa IU) for 7 days
versus
full-length graduated compression stocking for 7 days
patients undergoing knee arthroscopyopen (blinded assessment)
Follow-up duration: 3 months
Italy
Roth, 1995
0.3 ml sc fraxiparine 2 hours before the operation and self administered daily (except the firstvtwo doses) for 4 days after surgeryn/x
versus
no treatment
patients undergoing ambulatory arthroscopic
Follow-up duration: 4 days
Germany
nadroparin 14d versus control
KANT (14 days), 2008
once-daily subcutaneous injection of LMWH (nadroparin, 3800 anti-Xa IU) for 14 days
versus
full-length graduated compression stocking for 7 days
patients undergoing knee arthroscopy open (blinded assessment)
Follow-up duration: 3 months
Italy
reviparin versus control
Wirth, 2001
reviparin 1,750 anti Xa IU Sc once daily for 7-10 days
versus
no treatment
elective knee arthroscopyopen (blind assessement)
Follow-up duration: 7-10 days
Germany

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