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antithrombotics in percutaneous coronary intervention for patients with high residual platelet activity on clopidogrel, clinical trials results

high-dose clopidogrel versus normal-dose clopidogrel
GRAVITAS, 2011
NCT00645918
High-dose clopidogrel (600-mg initial dose, 150 mg daily thereafter)
versus
regular clopidogrel dose
patients receiving drug-eluting stents with high residual platelet activity (PRU>=230) on the regular clopidogrel dose (platelet-function tests with the VerifyNow assay 12 to 24 hours after PCI)open
Follow-up duration: 6 months
North America

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